FANCD2 influences replication fork processes and genome stability in response to clustered DSBs

Fanconi Anemia (FA) is a cancer predisposition syndrome and the factors defective in FA are involved in DNA replication, DNA damage repair and tumor suppression. Here, we show that FANCD2 is critical for genome stability maintenance in response to high-linear energy transfer (LET) radiation. We foun...

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Detalles Bibliográficos
Autores principales: Zhu, Jiayun, Su, Fengtao, Mukherjee, Shibani, Mori, Eiichiro, Hu, Burong, Asaithamby, Aroumougame
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613663/
https://www.ncbi.nlm.nih.gov/pubmed/26083937
http://dx.doi.org/10.1080/15384101.2015.1036210

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