Cargando…
Identification of a mitochondrial-binding site on the N-terminal end of hexokinase II
Hexokinase II (HKII) is responsible for the first step in the glycolysis pathway by adding a phosphate on to the glucose molecule so it can proceed down the pathway to produce the energy for continuous cancer cell growth. Tumour cells overexpress the HKII enzyme. In fact, it is the overexpression of...
Autores principales: | Bryan, Nadezda, Raisch, Kevin P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613670/ https://www.ncbi.nlm.nih.gov/pubmed/26182367 http://dx.doi.org/10.1042/BSR20150047 |
Ejemplares similares
-
Chlamydia trachomatis Prevents Apoptosis Via Activation of PDPK1-MYC and Enhanced Mitochondrial Binding of Hexokinase II
por: Al-Zeer, Munir A., et al.
Publicado: (2017) -
A study on the two binding sites of hexokinase on brain mitochondria
por: Golestani, Abolfazl, et al.
Publicado: (2007) -
Identification of RNA 3´ ends and termination sites in Haloferax volcanii
por: Berkemer, Sarah J., et al.
Publicado: (2020) -
Cyclophilin D ablation is associated with increased end-ischemic mitochondrial hexokinase activity
por: Nederlof, Rianne, et al.
Publicado: (2017) -
Hypothermia Prevents Cardiac Dysfunction during Acute Ischemia Reperfusion by Maintaining Mitochondrial Bioenergetics and by Promoting Hexokinase II Binding to Mitochondria
por: Sun, Jie, et al.
Publicado: (2022)