The class II transactivator (CIITA) is regulated by post-translational modification cross-talk between ERK1/2 phosphorylation, mono-ubiquitination and Lys(63) ubiquitination

The class II transactivator (CIITA) is known as the master regulator for the major histocompatibility class II (MHC II) molecules. CIITA is dynamically regulated through a series of intricate post-translational modifications (PTMs). CIITA's role is to initiate transcription of MHC II genes, whi...

Descripción completa

Detalles Bibliográficos
Autores principales: Morgan, Julie E., Shanderson, Ronald L., Boyd, Nathaniel H., Cacan, Ercan, Greer, Susanna F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613680/
https://www.ncbi.nlm.nih.gov/pubmed/26181363
http://dx.doi.org/10.1042/BSR20150091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613680/
https://www.ncbi.nlm.nih.gov/pubmed/26181363
http://dx.doi.org/10.1042/BSR20150091

Ejemplares similares