Cargando…

Osteoprotective effect of combination therapy of low-dose oestradiol with G15, a specific antagonist of GPR30/GPER in ovariectomy-induced osteoporotic rats

Identified and cloned in 1996 for the first time, G protein-coupled oestrogen receptor (ER) 30 (GPR30/GPER) has been a hot spot in the field of sex hormone research till now. In the present study, we examined the effects of low-dose oestradiol (E2) combined with G15, a specific antagonist of GPR30 o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kang, Wen-Bo, Cong, Yu, Ru, Jiang-Ying, Ying, Si-Qi, Zhu, Ting, Wang, Dong-Sheng, Liu, Xiao-Wei, Liu, Gang, Zhao, Jian-Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2015
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613688/ https://www.ncbi.nlm.nih.gov/pubmed/26181370 http://dx.doi.org/10.1042/BSR20150146

Ejemplares similares

Osteoprotective Effect of Echinocystic Acid, a Triterpone Component from Eclipta prostrata, in Ovariectomy-Induced Osteoporotic Rats
por: Deng, Ya-ting, et al.
Publicado: (2015)

G-protein Coupled Estrogen Receptor (GPER/GPR30) and Women's Health
por: Kim, Mi-Jin, et al.
Publicado: (2015)

Activation of the G-protein-coupled receptor GPR30 induces anxiogenic effects in mice, similar to oestradiol
por: Kastenberger, Iris, et al.
Publicado: (2011)

Enhanced expression of G-protein coupled estrogen receptor (GPER/GPR30) in lung cancer
por: Jala, Venkatakrishna Rao, et al.
Publicado: (2012)

The G-Protein-Coupled Estrogen Receptor (GPER/GPR30) in Ovarian Granulosa Cell Tumors
por: Heublein, Sabine, et al.
Publicado: (2014)

17β-oestradiol inhibits ferroptosis in the hippocampus by upregulating DHODH and further improves memory decline after ovariectomy
por: Tian, Ying, et al.
Publicado: (2023)

A Novel Mechanism of S-equol Action in Neurons and Astrocytes: The Possible Involvement of GPR30/GPER1
por: Ariyani, Winda, et al.
Publicado: (2019)

In vivo Effects of a GPR30 Antagonist
por: Dennis, Megan K., et al.
Publicado: (2009)

The G protein-coupled estrogen receptor 1 (GPER/GPR30) does not predict survival in patients with ovarian cancer
por: Kolkova, Zuzana, et al.
Publicado: (2012)

Genetic Variants of GPER/GPR30, a Novel Estrogen-Related G Protein Receptor, Are Associated with Human Seminoma
por: Chevalier, Nicolas, et al.
Publicado: (2014)

Osteoprotective Roles of Green Tea Catechins
por: Huang, Hsuan-Ti, et al.
Publicado: (2020)

Expression and Role of the G Protein-Coupled Estrogen Receptor (GPR30/GPER) in the Development and Immune Response in Female Reproductive Cancers
por: Hernández-Silva, Christian David, et al.
Publicado: (2020)

Effects of genistein aglycone in osteoporotic, ovariectomized rats: a comparison with alendronate, raloxifene and oestradiol
por: Bitto, A, et al.
Publicado: (2008)

Both GPER and membrane oestrogen receptor-α activation protect ventricular remodelling in 17β oestradiol-treated ovariectomized infarcted rats
por: Lee, Tsung-Ming, et al.
Publicado: (2014)

GPER1 (GPR30) knockout mice display reduced anxiety and altered stress response in a sex and paradigm dependent manner
por: Kastenberger, Iris, et al.
Publicado: (2014)

Synthesis and Characterization of Tricarbonyl-Re/Tc(I) Chelate Probes Targeting the G Protein-Coupled Estrogen Receptor GPER/GPR30
por: Burai, Ritwik, et al.
Publicado: (2012)

Characterisation of Signalling by the Endogenous GPER1 (GPR30) Receptor in an Embryonic Mouse Hippocampal Cell Line (mHippoE-18)
por: Evans, Nicholas J., et al.
Publicado: (2016)

The G-Protein Coupled Estrogen Receptor (GPER/GPR30) is a Gonadotropin Receptor Dependent Positive Prognosticator in Ovarian Carcinoma Patients
por: Heublein, Sabine, et al.
Publicado: (2013)

Concern and Risk Perception: Effects on Osteoprotective Behaviour
por: Barcenilla-Wong, A. L., et al.
Publicado: (2014)

An Ovariectomy-Induced Rabbit Osteoporotic Model: A New Perspective
por: Wanderman, Nathan Robert, et al.
Publicado: (2018)

Oestradiol-17β plasma concentrations after intramuscular injection of oestradiol benzoate or oestradiol cypionate in llamas (Lama glama)
por: Cavilla, María V, et al.
Publicado: (2010)

Eight new phenolic acids from the leaves of Illicium dunnianum and their osteoprotective activities
por: Li, Hai-bo, et al.
Publicado: (2022)

Plasma membrane expression of G protein-coupled estrogen receptor (GPER)/G protein-coupled receptor 30 (GPR30) is associated with worse outcome in metachronous contralateral breast cancer
por: Tutzauer, Julia, et al.
Publicado: (2020)

The osteoprotective effect of Herba epimedii (HEP) extract in vivo and in vitro
por: Xie, Fang, et al.
Publicado: (2005)

Osteoprotective effect of extract from Achyranthes japonica in ovariectomized rats
por: Kim, Jin-sung, et al.
Publicado: (2014)

The Osteoprotective Effects Of Kaempferol: The Evidence From In Vivo And In Vitro Studies
por: Wong, Sok Kuan, et al.
Publicado: (2019)

The osteoprotective role of USP26 in coordinating bone formation and resorption
por: Li, Changwei, et al.
Publicado: (2022)

Effect of 50-Hertz Sinusoidal Vibration on the Uterus in Ovariectomy-Induced Osteoporotic Rats
por: Zhang, Yanfang, et al.
Publicado: (2022)

Osteoprotective Effect of Cordycepin on Estrogen Deficiency-Induced Osteoporosis In Vitro and In Vivo
por: Zhang, Da-wei, et al.
Publicado: (2015)

Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism
por: Cao, Sisi, et al.
Publicado: (2018)

Study of Endothelio- and Osteoprotective Effects of Combination of Rosuvastatin with L-Norvaline in Experiment
por: Sobolev, M. S., et al.
Publicado: (2018)

Retracted: Effect of 50-Hertz Sinusoidal Vibration on the Uterus in Ovariectomy-Induced Osteoporotic Rats
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

3-OBA Is Not an Antagonist of GPR81
por: Mohammad Nezhady, Mohammad Ali, et al.
Publicado: (2022)

NHERF1, a novel GPER associated protein, increases stability and activation of GPER in ER-positive breast cancer
por: Meng, Ran, et al.
Publicado: (2016)

17β-Estradiol on the Expression of G-Protein Coupled Estrogen Receptor (GPER/GPR30) Mitophagy, and the PI3K/Akt Signaling Pathway in ATDC5 Chondrocytes In Vitro
por: Fan, Dong-xiao, et al.
Publicado: (2018)

Osteoprotective effects of Fructus Ligustri Lucidi aqueous extract in aged ovariectomized rats
por: Ko, Chun Hay, et al.
Publicado: (2010)

Osteoprotective Effects of Loganic Acid on Osteoblastic and Osteoclastic Cells and Osteoporosis-Induced Mice
por: Park, Eunkuk, et al.
Publicado: (2020)

Revisiting Resveratrol as an Osteoprotective Agent: Molecular Evidence from In Vivo and In Vitro Studies
por: Ahmad Hairi, Haryati, et al.
Publicado: (2023)

ɶstradiol Benzoate Therapy in Senile Vaginitis
por: Macgregor, T. N.
Publicado: (1938)

Systemic osteoprotective effects of Epimedii Folium and Ligustri Lucidi Fructus in senile osteoporosis rats by promoting the osteoblastogenesis and osteoclastogenesis based on MLP-ANN model
por: Tang, Xiu-Feng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_kn71slq3mnnch6n01s5mdpgdfo