Cargando…

Reciprocal inhibition between miR-26a and NF-κB regulates obesity-related chronic inflammation in chondrocytes

Obesity is causally linked to osteoarthritis (OA), with the mechanism being not fully elucidated. miRNAs (miRs) are pivotal regulators of various diseases in multiple tissues, including inflammation in the chondrocytes. In the present study, we for the first time identified the expression of miR-26a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Qingyun, Wei, Meng, Kang, Xia, Liu, Da, Quan, Yi, Pan, Xianming, Liu, Xiling, Liao, Dongfa, Liu, Jinbiao, Zhang, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2015
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613702/ https://www.ncbi.nlm.nih.gov/pubmed/26182366 http://dx.doi.org/10.1042/BSR20150071

Ejemplares similares

Icariin inhibits the inflammation through down-regulating NF-κB/HIF-2α signal pathways in chondrocytes
por: Wang, Pengzhen, et al.
Publicado: (2020)

Fxyd5 activates the NF-κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation
por: Song, Lulu, et al.
Publicado: (2022)

Cepharanthine Ameliorates Chondrocytic Inflammation and Osteoarthritis via Regulating the MAPK/NF-κB-Autophagy Pathway
por: Yao, Minjun, et al.
Publicado: (2022)

NF-κB signaling in inflammation
por: Liu, Ting, et al.
Publicado: (2017)

Schisandrin B ameliorated chondrocytes inflammation and osteoarthritis via suppression of NF-κB and MAPK signal pathways
por: Ran, Jisheng, et al.
Publicado: (2018)

Phillygenin inhibits inflammation in chondrocytes via the Nrf2/NF-κB axis and ameliorates osteoarthritis in mice
por: Zhang, Peng, et al.
Publicado: (2023)

Synovial tissue‐derived extracellular vesicles induce chondrocyte inflammation and degradation via NF‐κB signalling pathway: An in vitro study
por: Chen, Pu, et al.
Publicado: (2022)

NF-κB-Regulated miR-99a Modulates Endothelial Cell Inflammation
por: Bao, Mei-hua, et al.
Publicado: (2016)

Abnormal expression of miR-4784 in chondrocytes of osteoarthritis and associations with chondrocyte hyperplasia
por: Liu, Jing, et al.
Publicado: (2018)

Icariin Activates Autophagy via Down-Regulation of the NF-κB Signaling-Mediated Apoptosis in Chondrocytes
por: Mi, Bobin, et al.
Publicado: (2018)

miR-125b and miR-223 Contribute to Inflammation by Targeting the Key Molecules of NFκB Pathway
por: Valmiki, Swati, et al.
Publicado: (2020)

MiR-4303 relieves chondrocyte inflammation by targeting ASPN in osteoarthritis
por: Wang, Chunyu, et al.
Publicado: (2021)

Reciprocal Role of ERK and Nf-κb Pathways in Survival and Activation of Osteoclasts
por: Miyazaki, Tsuyoshi, et al.
Publicado: (2000)

Trans-Cinnamaldehyde Inhibits IL-1β-Stimulated Inflammation in Chondrocytes by Suppressing NF-κB and p38-JNK Pathways and Exerts Chondrocyte Protective Effects in a Rat Model of Osteoarthritis
por: Xia, Tianwei, et al.
Publicado: (2019)

Reciprocal interplay between OTULIN–LUBAC determines genotoxic and inflammatory NF-κB signal responses
por: Li, Mingqi, et al.
Publicado: (2022)

Kaempferol Alleviates the Interleukin-1β-Induced Inflammation in Rat Osteoarthritis Chondrocytes via Suppression of NF-κB
por: Zhuang, Zhengling, et al.
Publicado: (2017)

Morusin Ameliorates IL-1β-Induced Chondrocyte Inflammation and Osteoarthritis via NF-κB Signal Pathway
por: Jia, Yewei, et al.
Publicado: (2020)

Curcumenol mitigates chondrocyte inflammation by inhibiting the NF-κB and MAPK pathways, and ameliorates DMM-induced OA in mice
por: Yang, Xiao, et al.
Publicado: (2021)

Platelet-rich plasma inhibits Adriamycin-induced inflammation via blocking the NF-κB pathway in articular chondrocytes
por: Zhao, Haijun, et al.
Publicado: (2021)

Indole-3-propionic acid alleviates chondrocytes inflammation and osteoarthritis via the AhR/NF-κB axis
por: Zhuang, Huangming, et al.
Publicado: (2023)

Naringenin attenuates inflammation and apoptosis of osteoarthritic chondrocytes via the TLR4/TRAF6/NF-κB pathway
por: Wang, Yan, et al.
Publicado: (2023)

Ononin ameliorates inflammation and cartilage degradation in rat chondrocytes with IL-1β-induced osteoarthritis by downregulating the MAPK and NF-κB pathways
por: Xu, Fang, et al.
Publicado: (2022)

miR‐640 aggravates intervertebral disc degeneration via NF‐κB and WNT signalling pathway
por: Dong, Wengang, et al.
Publicado: (2019)

MiR-19b-3p Attenuates Chondrocytes Injury by Inhibiting MAPK/NF-Κb Axis via Targeting SOCS1
por: Shi, Liang, et al.
Publicado: (2022)

CircTBX5 knockdown modulates the miR-558/MyD88 axis to alleviate IL-1β-induced inflammation, apoptosis and extracellular matrix degradation in chondrocytes via inactivating the NF-κB signaling
por: Wei, Wei, et al.
Publicado: (2023)

Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation
por: Deng, Yujie, et al.
Publicado: (2018)

MicroRNA-93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NF-κB signaling pathway
por: Ding, Yanjie, et al.
Publicado: (2019)

Silencing of Vangl2 attenuates the inflammation promoted by Wnt5a via MAPK and NF-κB pathway in chondrocytes
por: Zhang, Ke, et al.
Publicado: (2021)

Dihydroartemisinin inhibits catabolism in rat chondrocytes by activating autophagy via inhibition of the NF-κB pathway
por: Jiang, Li-Bo, et al.
Publicado: (2016)

miR-26b Targets CEP135 Gene to Regulate Nasopharyngeal Carcinoma Proliferation and Migration by NF-κB Pathway
por: Yang, Guangrun, et al.
Publicado: (2023)

Retracted: MiR-19b-3p Attenuates Chondrocytes Injury by Inhibiting MAPK/NF-Κb Axis via Targeting SOCS1
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

MFG-E8 regulated by miR-99b-5p protects against osteoarthritis by targeting chondrocyte senescence and macrophage reprogramming via the NF-κB pathway
por: Lu, Yuheng, et al.
Publicado: (2021)

MiR-128-3p Post-Transcriptionally Inhibits WISP1 to Suppress Apoptosis and Inflammation in Human Articular Chondrocytes via the PI3K/AKT/NF-κB Signaling Pathway
por: Chen, Shujun, et al.
Publicado: (2020)

MiR‐802 causes nephropathy by suppressing NF‐κB‐repressing factor in obese mice and human
por: Sun, Da, et al.
Publicado: (2019)

Kaempferide improves oxidative stress and inflammation by inhibiting the TLR4/IκBα/NF-κB pathway in obese mice
por: Tang, Heng, et al.
Publicado: (2021)

Nobiletin Inhibits IL-1β-Induced Inflammation in Chondrocytes via Suppression of NF-κB Signaling and Attenuates Osteoarthritis in Mice
por: Lin, Zeng, et al.
Publicado: (2019)

Resveratrol alleviates the interleukin-1β-induced chondrocytes injury through the NF-κB signaling pathway
por: Yi, Hong, et al.
Publicado: (2020)

NF-κB activation impedes the transdifferentiation of hypertrophic chondrocytes at the growth plate of mouse embryos in diabetic pregnancy
por: Liu, Xi, et al.
Publicado: (2021)

miR-130b, an onco-miRNA in bladder cancer, is directly regulated by NF-κB and sustains NF-κB activation by decreasing Cylindromatosis expression
por: Cui, Xiaolu, et al.
Publicado: (2016)

NF-κB signaling in tanycytes mediates inflammation-induced anorexia
por: Böttcher, Mareike, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8fa20f8gu9q77h25gen1ca1bf8