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Effect of BIX-01294 on H3K9me2 levels and the imprinted gene Snrpn in mouse embryonic fibroblast cells

Histone H3 lysine 9 dimethylation (H3K9me2) hypermethylation is thought to be a major influential factor in cellular reprogramming, such as somatic cell nuclear transfer (SCNT) and induction of pluripotent stem cells (iPSCs). The diazepin-quinazolin-amine derivative (BIX-01294) specifically inhibits...

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Detalles Bibliográficos
Autores principales:	Chen, Peng, Yao, Jian-Feng, Huang, Rong-Fu, Zheng, Fang-Fang, Jiang, Xiao-Hong, Chen, Xuan, Chen, Juan, Li, Ming, Huang, Hong-Feng, Jiang, Yi-Ping, Huang, Yan-Fang, Yang, Xiao-Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2015
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613706/ https://www.ncbi.nlm.nih.gov/pubmed/26285804 http://dx.doi.org/10.1042/BSR20150064

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