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Genetic variants affecting human TRPA1 or TRPM8 structure can be classified in vitro as ‘well expressed’, ‘poorly expressed’ or ‘salvageable’

Multiple mis-sense variants of TRPA1 (transient receptor potential A1) and TRPM8 (transient receptor potential M8) are recorded in the human genome single nt polymorphism (SNP) database, but their potential impact on channel signalling in patho-physiology is not fully explored. Variants, mostly quit...

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Detalles Bibliográficos
Autores principales:	Morgan, Kevin, Sadofsky, Laura Rachel, Morice, Alyn Hugh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2015
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613725/ https://www.ncbi.nlm.nih.gov/pubmed/26330615 http://dx.doi.org/10.1042/BSR20150108

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