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Hepatic S1P deficiency lowers plasma cholesterol levels in apoB-containing lipoproteins when LDLR function is compromised

BACKGROUND: Site-1 protease (S1P) is the key enzyme required for activation of the sterol regulatory element binding proteins (SREBPs) that govern lipid synthesis. While S1P has been speculated to influence plasma apoB-containing lipoprotein (Blp) metabolism, there has been little investigative work...

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Detalles Bibliográficos
Autores principales:	Basu, Debapriya, Huq, Afroza, Iqbal, Jahangir, Hussain, M. Mahmood, Jiang, Xian-Cheng, Jin, Weijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613744/ https://www.ncbi.nlm.nih.gov/pubmed/26495026 http://dx.doi.org/10.1186/s12986-015-0031-4

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