Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo

Prior studies have implicated accumulation of ceramide in blood vessels as a basis for vascular dysfunction in diet-induced obesity via a mechanism involving type 2 protein phosphatase (PP2A) dephosphorylation of endothelial nitric oxide synthase (eNOS). The current study sought to elucidate the mec...

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Detalles Bibliográficos
Autores principales: Bharath, Leena P., Ruan, Ting, Li, Youyou, Ravindran, Anindita, Wan, Xin, Nhan, Jennifer Kim, Walker, Matthew Lewis, Deeter, Lance, Goodrich, Rebekah, Johnson, Elizabeth, Munday, Derek, Mueller, Robert, Kunz, David, Jones, Deborah, Reese, Van, Summers, Scott A., Babu, Pon Velayutham Anandh, Holland, William L., Zhang, Quan-Jiang, Abel, E. Dale, Symons, J. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613970/
https://www.ncbi.nlm.nih.gov/pubmed/26253611
http://dx.doi.org/10.2337/db15-0244

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