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Gpr17 in AgRP Neurons Regulates Feeding and Sensitivity to Insulin and Leptin

Hypothalamic neurons expressing agouti-related peptide (AgRP) regulate eating and glucose metabolism. Ablation of FOXO1 in AgRP neurons of mice results in reduced food intake, leanness, improved glucose homeostasis, and increased sensitivity to insulin and leptin. We tentatively identified G-protein...

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Detalles Bibliográficos
Autores principales:	Ren, Hongxia, Cook, Joshua R., Kon, Ning, Accili, Domenico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2015
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613971/ https://www.ncbi.nlm.nih.gov/pubmed/26180086 http://dx.doi.org/10.2337/db15-0390

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