MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function

Insulin produced by islet β-cells plays a critical role in glucose homeostasis, with type 1 and type 2 diabetes both resulting from inactivation and/or loss of this cell population. Islet-enriched transcription factors regulate β-cell formation and function, yet little is known about the molecules r...

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Detalles Bibliográficos
Autores principales: Scoville, David W., Cyphert, Holly A., Liao, Lan, Xu, Jianming, Reynolds, Al, Guo, Shuangli, Stein, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613979/
https://www.ncbi.nlm.nih.gov/pubmed/26180087
http://dx.doi.org/10.2337/db15-0281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613979/
https://www.ncbi.nlm.nih.gov/pubmed/26180087
http://dx.doi.org/10.2337/db15-0281

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