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Evidence for a CDK4-dependent checkpoint in a conditional model of cellular senescence

Cellular senescence, the stable cell cycle arrest elicited by various forms of stress, is an important facet of tumor suppression. Although much is known about the key players in the implementation of senescence, including the pRb and p53 axes and the cyclin dependent kinase inhibitors p16(INK4a) an...

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Detalles Bibliográficos
Autores principales:	Brookes, Sharon, Gagrica, Sladjana, Sanij, Elaine, Rowe, Janice, Gregory, Fiona J, Hara, Eiji, Peters, Gordon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613988/ https://www.ncbi.nlm.nih.gov/pubmed/25695870 http://dx.doi.org/10.1080/15384101.2015.1010866

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