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Can Serum be Used for Analyzing the KRAS Mutation Status in Patients with Advanced Colorectal Cancer?

PURPOSE: KRAS mutations have been used widely as prognostic or predictive marker in patients with advanced colorectal cancer (CRC). However, it may be difficult to obtain a tumor tissue for analyzing the status of KRAS mutation in large proportion of patients with advanced disease. MATERIALS AND MET...

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Detalles Bibliográficos
Autores principales: Kim, Seung Tae, Chang, Won Jin, Jin, Lihua, Sung, Jae Sook, Choi, Yun Ji, Kim, Yeul Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614179/
https://www.ncbi.nlm.nih.gov/pubmed/25687873
http://dx.doi.org/10.4143/crt.2014.106