Flare-up reactions in severe drug hypersensitivity: infection or ongoing T-cell hyperresponsiveness

“Flare-up” reactions are late manifestations of severe T-cell-mediated drug hypersensitivity reactions. Management is anti-inflammatory treatment and avoiding unnecessary medicines. Symptoms like fever, lymph node swelling, and blood count abnormalities may lead to confusion with bacterial infection...

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Detalles Bibliográficos
Autores principales: Jörg-Walther, Lukas, Schnyder, Benno, Helbling, Arthur, Helsing, Karin, Schüller, Alexandra, Wochner, Annette, Pichler, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614642/
https://www.ncbi.nlm.nih.gov/pubmed/26509009
http://dx.doi.org/10.1002/ccr3.346
Descripción
Sumario:“Flare-up” reactions are late manifestations of severe T-cell-mediated drug hypersensitivity reactions. Management is anti-inflammatory treatment and avoiding unnecessary medicines. Symptoms like fever, lymph node swelling, and blood count abnormalities may lead to confusion with bacterial infections. For prompt recognition it is important to keep the differential diagnosis in mind.

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