Diagnosis of intrachromosomal amplification of chromosome 21 (iAMP21) by molecular cytogenetics in pediatric acute lymphoblastic leukemia

Intrachromosomal amplification of chromosome 21 (iAMP21) defines a distinct cytogenetic subgroup of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) with poor prognosis that should be investigated in routine practice. Single-nucleotide polymorphism (SNP)-array provides a useful method to dete...

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Autores principales: Duployez, Nicolas, Boudry-Labis, Elise, Decool, Gauthier, Grzych, Guillaume, Grardel, Nathalie, Abou Chahla, Wadih, Preudhomme, Claude, Roche-Lestienne, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614646/
https://www.ncbi.nlm.nih.gov/pubmed/26509013
http://dx.doi.org/10.1002/ccr3.357
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author Duployez, Nicolas
Boudry-Labis, Elise
Decool, Gauthier
Grzych, Guillaume
Grardel, Nathalie
Abou Chahla, Wadih
Preudhomme, Claude
Roche-Lestienne, Catherine
author_facet Duployez, Nicolas
Boudry-Labis, Elise
Decool, Gauthier
Grzych, Guillaume
Grardel, Nathalie
Abou Chahla, Wadih
Preudhomme, Claude
Roche-Lestienne, Catherine
author_sort Duployez, Nicolas
collection PubMed
description Intrachromosomal amplification of chromosome 21 (iAMP21) defines a distinct cytogenetic subgroup of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) with poor prognosis that should be investigated in routine practice. Single-nucleotide polymorphism (SNP)-array provides a useful method to detect such cases showing a highly characteristic profile.
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spelling pubmed-46146462015-10-27 Diagnosis of intrachromosomal amplification of chromosome 21 (iAMP21) by molecular cytogenetics in pediatric acute lymphoblastic leukemia Duployez, Nicolas Boudry-Labis, Elise Decool, Gauthier Grzych, Guillaume Grardel, Nathalie Abou Chahla, Wadih Preudhomme, Claude Roche-Lestienne, Catherine Clin Case Rep Case Reports Intrachromosomal amplification of chromosome 21 (iAMP21) defines a distinct cytogenetic subgroup of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) with poor prognosis that should be investigated in routine practice. Single-nucleotide polymorphism (SNP)-array provides a useful method to detect such cases showing a highly characteristic profile. John Wiley & Sons, Ltd 2015-10 2015-08-26 /pmc/articles/PMC4614646/ /pubmed/26509013 http://dx.doi.org/10.1002/ccr3.357 Text en © 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Duployez, Nicolas
Boudry-Labis, Elise
Decool, Gauthier
Grzych, Guillaume
Grardel, Nathalie
Abou Chahla, Wadih
Preudhomme, Claude
Roche-Lestienne, Catherine
Diagnosis of intrachromosomal amplification of chromosome 21 (iAMP21) by molecular cytogenetics in pediatric acute lymphoblastic leukemia
title Diagnosis of intrachromosomal amplification of chromosome 21 (iAMP21) by molecular cytogenetics in pediatric acute lymphoblastic leukemia
title_full Diagnosis of intrachromosomal amplification of chromosome 21 (iAMP21) by molecular cytogenetics in pediatric acute lymphoblastic leukemia
title_fullStr Diagnosis of intrachromosomal amplification of chromosome 21 (iAMP21) by molecular cytogenetics in pediatric acute lymphoblastic leukemia
title_full_unstemmed Diagnosis of intrachromosomal amplification of chromosome 21 (iAMP21) by molecular cytogenetics in pediatric acute lymphoblastic leukemia
title_short Diagnosis of intrachromosomal amplification of chromosome 21 (iAMP21) by molecular cytogenetics in pediatric acute lymphoblastic leukemia
title_sort diagnosis of intrachromosomal amplification of chromosome 21 (iamp21) by molecular cytogenetics in pediatric acute lymphoblastic leukemia
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614646/
https://www.ncbi.nlm.nih.gov/pubmed/26509013
http://dx.doi.org/10.1002/ccr3.357
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