P16 and HPV discordance in metastatic carcinoma of cervical lymph nodes of unknown primary

The prognostic utility of HPV in oropharyngeal squamous cell carcinoma (OPSCC) and non-OPSCC as has been well documented. Currently, a standardized IHC scoring system does not exist and is needed to define HPV positivity. We have recently seen a patient that provides a caution in using p16 status as...

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Autores principales: Ralph, Alyssa, Meyer, Andrew, Sirota, Ronald, Hooberman, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614647/
https://www.ncbi.nlm.nih.gov/pubmed/26509014
http://dx.doi.org/10.1002/ccr3.338
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author Ralph, Alyssa
Meyer, Andrew
Sirota, Ronald
Hooberman, Arthur
author_facet Ralph, Alyssa
Meyer, Andrew
Sirota, Ronald
Hooberman, Arthur
author_sort Ralph, Alyssa
collection PubMed
description The prognostic utility of HPV in oropharyngeal squamous cell carcinoma (OPSCC) and non-OPSCC as has been well documented. Currently, a standardized IHC scoring system does not exist and is needed to define HPV positivity. We have recently seen a patient that provides a caution in using p16 status as a diagnostic aid.
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spelling pubmed-46146472015-10-27 P16 and HPV discordance in metastatic carcinoma of cervical lymph nodes of unknown primary Ralph, Alyssa Meyer, Andrew Sirota, Ronald Hooberman, Arthur Clin Case Rep Case Reports The prognostic utility of HPV in oropharyngeal squamous cell carcinoma (OPSCC) and non-OPSCC as has been well documented. Currently, a standardized IHC scoring system does not exist and is needed to define HPV positivity. We have recently seen a patient that provides a caution in using p16 status as a diagnostic aid. John Wiley & Sons, Ltd 2015-10 2015-09-02 /pmc/articles/PMC4614647/ /pubmed/26509014 http://dx.doi.org/10.1002/ccr3.338 Text en © 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Ralph, Alyssa
Meyer, Andrew
Sirota, Ronald
Hooberman, Arthur
P16 and HPV discordance in metastatic carcinoma of cervical lymph nodes of unknown primary
title P16 and HPV discordance in metastatic carcinoma of cervical lymph nodes of unknown primary
title_full P16 and HPV discordance in metastatic carcinoma of cervical lymph nodes of unknown primary
title_fullStr P16 and HPV discordance in metastatic carcinoma of cervical lymph nodes of unknown primary
title_full_unstemmed P16 and HPV discordance in metastatic carcinoma of cervical lymph nodes of unknown primary
title_short P16 and HPV discordance in metastatic carcinoma of cervical lymph nodes of unknown primary
title_sort p16 and hpv discordance in metastatic carcinoma of cervical lymph nodes of unknown primary
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614647/
https://www.ncbi.nlm.nih.gov/pubmed/26509014
http://dx.doi.org/10.1002/ccr3.338
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