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Characterization of clinically identified mutations in NDUFV1, the flavin-binding subunit of respiratory complex I, using a yeast model system

Dysfunctions in mitochondrial complex I (NADH:ubiquinone oxidoreductase) are both genetically and clinically highly diverse and a major cause of human mitochondrial diseases. The genetic determinants of individual clinical cases are increasingly being described, but how these genetic defects affect...

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Detalles Bibliográficos
Autores principales:	Varghese, Febin, Atcheson, Erwan, Bridges, Hannah R., Hirst, Judy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614703/ https://www.ncbi.nlm.nih.gov/pubmed/26345448 http://dx.doi.org/10.1093/hmg/ddv344

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