Cargando…

Mesenchymal Stem Cells Reduce Murine Atherosclerosis Development

Mesenchymal stem cells (MSCs) have regenerative properties, but recently they were also found to have immunomodulatory capacities. We therefore investigated whether MSCs could reduce atherosclerosis, which is determined by dyslipidaemia and chronic inflammation. We adoptively transferred MSCs into l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Frodermann, Vanessa, van Duijn, Janine, van Pel, Melissa, van Santbrink, Peter J., Bot, Ilze, Kuiper, Johan, de Jager, Saskia C. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614841/ https://www.ncbi.nlm.nih.gov/pubmed/26490642 http://dx.doi.org/10.1038/srep15559

Ejemplares similares

Agonistic Anti-TIGIT Treatment Inhibits T Cell Responses in LDLr Deficient Mice without Affecting Atherosclerotic Lesion Development
por: Foks, Amanda C., et al.
Publicado: (2013)

Tc17 CD8(+) T cells accumulate in murine atherosclerotic lesions, but do not contribute to early atherosclerosis development
por: van Duijn, Janine, et al.
Publicado: (2020)

Defective Autophagy in T Cells Impairs the Development of Diet-Induced Hepatic Steatosis and Atherosclerosis
por: Amersfoort, Jacob, et al.
Publicado: (2018)

Inhibition of lysophosphatidic acid receptors 1 and 3 attenuates atherosclerosis development in LDL-receptor deficient mice
por: Kritikou, Eva, et al.
Publicado: (2016)

Leukocytosis and Enhanced Susceptibility to Endotoxemia but Not Atherosclerosis in Adrenalectomized APOE Knockout Mice
por: Hoekstra, Menno, et al.
Publicado: (2013)

Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective T-cell responsiveness
por: Ellenbroek, Guilielmus H.J.M., et al.
Publicado: (2017)

Flow Cytometry-Based Characterization of Mast Cells in Human Atherosclerosis
por: Kritikou, Eva, et al.
Publicado: (2019)

Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis
por: de Jager, Saskia C.A., et al.
Publicado: (2011)

Hematopoietic Sphingosine 1-Phosphate Lyase Deficiency Decreases Atherosclerotic Lesion Development in LDL-Receptor Deficient Mice
por: Bot, Martine, et al.
Publicado: (2013)

Stress-induced mast cell activation contributes to atherosclerotic plaque destabilization
por: Lagraauw, H. Maxime, et al.
Publicado: (2019)

Blockade of the BLT1-LTB(4) axis does not affect mast cell migration towards advanced atherosclerotic lesions in LDLr(−/−) mice
por: Depuydt, Marie A. C., et al.
Publicado: (2022)

Mesenchymal stem cells in autoimmune diseases: hype or hope?
por: Scherer, Hans U, et al.
Publicado: (2010)

Mutation in KERA Identified by Linkage Analysis and Targeted Resequencing in a Pedigree with Premature Atherosclerosis
por: Maiwald, Stephanie, et al.
Publicado: (2014)

Induction of HLA-A2 restricted CD8 T cell responses against ApoB100 peptides does not affect atherosclerosis in a humanized mouse model
por: Schaftenaar, Frank H., et al.
Publicado: (2019)

IFNγ-Stimulated B Cells Inhibit T Follicular Helper Cells and Protect Against Atherosclerosis
por: Douna, Hidde, et al.
Publicado: (2022)

Diet-induced dyslipidemia induces metabolic and migratory adaptations in regulatory T cells
por: Amersfoort, Jacob, et al.
Publicado: (2020)

CD1d deficiency inhibits the development of abdominal aortic aneurysms in LDL receptor deficient mice
por: van Puijvelde, Gijs H. M., et al.
Publicado: (2018)

Inhibition of microRNA-494-3p activates Wnt signaling and reduces proinflammatory macrophage polarization in atherosclerosis
por: van Ingen, Eva, et al.
Publicado: (2021)

Single-cell profiling reveals age-associated immunity in atherosclerosis
por: Smit, Virginia, et al.
Publicado: (2023)

Mast cell depletion in the preclinical phase of collagen-induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile
por: van der Velden, Daniël, et al.
Publicado: (2016)

Acute and chronic effects of treatment with mesenchymal stromal cells on LPS-induced pulmonary inflammation, emphysema and atherosclerosis development
por: Khedoe, P. Padmini S. J., et al.
Publicado: (2017)

Antisense Oligonucleotide Inhibition of MicroRNA-494 Halts Atherosclerotic Plaque Progression and Promotes Plaque Stabilization
por: van Ingen, Eva, et al.
Publicado: (2019)

A novel CCR2 antagonist inhibits atherogenesis in apoE deficient mice by achieving high receptor occupancy
por: Bot, Ilze, et al.
Publicado: (2017)

Local Mast Cell Activation Promotes Neovascularization
por: Bot, Ilze, et al.
Publicado: (2020)

Hematopoietic upstream stimulating factor 1 deficiency is associated with increased atherosclerosis susceptibility in LDL receptor knockout mice
por: Hoekstra, Menno, et al.
Publicado: (2021)

Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells
por: Fontaine, Margaux A. C., et al.
Publicado: (2019)

Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis
por: Segers, Filip M E, et al.
Publicado: (2022)

Mesenchymal stem cell transplantation alleviated atherosclerosis in systemic lupus erythematosus through reducing MDSCs
por: Yao, Genhong, et al.
Publicado: (2022)

Complement factor C5a induces atherosclerotic plaque disruptions
por: Wezel, Anouk, et al.
Publicado: (2014)

THE ULTRASTRUCTURAL LOCALIZATION OF THE ISOZYMES OF ASPARTATE AMINOTRANSFERASE IN MURINE TISSUES
por: Papadimitriou, J. M., et al.
Publicado: (1970)

Function and Therapeutic Potential of Mesenchymal Stem Cells in Atherosclerosis
por: Li, Feifei, et al.
Publicado: (2017)

An Improved Harvest and in Vitro Expansion Protocol for Murine Bone Marrow-Derived Mesenchymal Stem Cells
por: Xu, Song, et al.
Publicado: (2010)

Human amnion mesenchymal stem cells attenuate atherosclerosis by modulating macrophage function to reduce immune response
por: Wei, Xiufang, et al.
Publicado: (2019)

Circulating Immunoglobulins Are Not Associated with Intraplaque Mast Cell Number and Other Vulnerable Plaque Characteristics in Patients with Carotid Artery Stenosis
por: Willems, Sanne, et al.
Publicado: (2014)

Mast Cells: Pivotal Players in Cardiovascular Diseases
por: Bot, Ilze, et al.
Publicado: (2008)

B cell depletion reduces the development of atherosclerosis in mice
por: Ait-Oufella, Hafid, et al.
Publicado: (2010)

Low-dose oral cyclophosphamide therapy reduces atherosclerosis progression by decreasing inflammatory cells in a murine model of atherosclerosis
por: Sato-Okabayashi, Yayoi, et al.
Publicado: (2020)

Cytokine‐induced hematopoietic stem and progenitor cell mobilization: unraveling interactions between stem cells and their niche
por: de Kruijf, Evert‐Jan F.M., et al.
Publicado: (2019)

The Association Between Inflammation, Epithelial Mesenchymal Transition and Stemness in Colorectal Carcinoma
por: Briede, Inese, et al.
Publicado: (2020)

Stemness, Inflammation and Epithelial–Mesenchymal Transition in Colorectal Carcinoma: The Intricate Network
por: Briede, Inese, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0pcq1cmrgo31j21i3hb27k1h6p