Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics

Aberrations in the cyclin-dependent kinase (CDK) pathways that regulate the cell cycle restriction point contribute to genomic instability and tumor proliferation, and can be targeted by recently developed CDK inhibitors. We therefore investigated the clinical correlates of CDK4/6 and CDKN2A/B abnor...

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Detalles Bibliográficos
Autores principales: Kato, Shumei, Schwaederle, Maria, Daniels, Gregory A, Piccioni, David, Kesari, Santosh, Bazhenova, Lyudmila, Shimabukuro, Kelly, Parker, Barbara A, Fanta, Paul, Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614867/
https://www.ncbi.nlm.nih.gov/pubmed/25695927
http://dx.doi.org/10.1080/15384101.2015.1014149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614867/
https://www.ncbi.nlm.nih.gov/pubmed/25695927
http://dx.doi.org/10.1080/15384101.2015.1014149

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