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The alternative translated MDMX(p60) isoform regulates MDM2 activity

Isoforms derived from alternative splicing, mRNA translation initiation or promoter usage extend the functional repertoire of the p53, p63 and p73 genes family and of their regulators MDM2 and MDMX. Here we show cap-independent translation of an N-terminal truncated isoform of hMDMX, hMDMX(p60), whi...

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Detalles Bibliográficos
Autores principales: Tournillon, Anne-Sophie, López, Ignacio, Malbert-Colas, Laurence, Naski, Nadia, Olivares-Illana, Vanesa, Fåhraeus, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615104/
https://www.ncbi.nlm.nih.gov/pubmed/25659040
http://dx.doi.org/10.4161/15384101.2014.977081