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Cell cycle control (and more) by programmed −1 ribosomal frameshifting: implications for disease and therapeutics
Like most basic molecular mechanisms, programmed –1 ribosomal frameshifting (−1 PRF) was first identified in viruses. Early observations that global dysregulation of −1 PRF had deleterious effects on yeast cell growth suggested that −1 PRF may be used to control cellular gene expression, and the cel...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615106/ https://www.ncbi.nlm.nih.gov/pubmed/25584829 http://dx.doi.org/10.4161/15384101.2014.989123 |