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Bimodal regulation of p21(waf1) protein as function of DNA damage levels

Human p21(Waf1) protein is well known for being transcriptionally induced by p53 and activating the cell cycle checkpoint arrest in response to DNA breaks. Here we report that p21(Waf1) protein undergoes a bimodal regulation, being upregulated in response to low doses of DNA damage but rapidly and t...

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Detalles Bibliográficos
Autores principales:	Buscemi, G, Ricci, C, Zannini, L, Fontanella, E, Plevani, P, Delia, D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2014
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615108/ https://www.ncbi.nlm.nih.gov/pubmed/25486478 http://dx.doi.org/10.4161/15384101.2014.946852

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