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KRAS, p53 and BRAF Gene Mutations and Aneuploidy in Sporadic Colorectal Cancer Progression

Background: The origin and mechanisms of chromosomal instability are still widely unknown. We previously investigated a limited number of human sporadic colorectal cancers (CRCs) and observed a statistically different occurrence of KRAS and p53 mutations among predetermined subgroups of tumors with...

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Detalles Bibliográficos
Autores principales: Calistri, Daniele, Rengucci, Claudia, Seymour, Ian, Leonardi, Elena, Truini, Mauro, Malacarne, Davide, Castagnola, Patrizio, Giaretti, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615153/
https://www.ncbi.nlm.nih.gov/pubmed/16988471
http://dx.doi.org/10.1155/2006/465050