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Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices
The presence of tumor cells in bone marrow, peripheral blood and lymph nodes has proven its clinical and prognostic value. Since the frequency of these cells in bone marrow and blood is sometimes as low as 1 per million and due to the fact that for the analysis of lymph nodes many sectioning levels...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615155/ https://www.ncbi.nlm.nih.gov/pubmed/16988469 http://dx.doi.org/10.1155/2006/610562 |
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author | Mesker, Wilma E. Vrolijk, Hans Sloos, Willem C. R. Tollenaar, Rob A. E. M. Tanke, Hans J. |
author_facet | Mesker, Wilma E. Vrolijk, Hans Sloos, Willem C. R. Tollenaar, Rob A. E. M. Tanke, Hans J. |
author_sort | Mesker, Wilma E. |
collection | PubMed |
description | The presence of tumor cells in bone marrow, peripheral blood and lymph nodes has proven its clinical and prognostic value. Since the frequency of these cells in bone marrow and blood is sometimes as low as 1 per million and due to the fact that for the analysis of lymph nodes many sectioning levels have to be analyzed, automated imaging devices have been suggested as an useful alternative to conventional manual screening of specimens. The aim of this paper is to review the performance of current equipment that is commercially available, based on literature published so far. Requirements for introducing this equipment for routine clinical practice are discussed. |
format | Online Article Text |
id | pubmed-4615155 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | IOS Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-46151552016-01-12 Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices Mesker, Wilma E. Vrolijk, Hans Sloos, Willem C. R. Tollenaar, Rob A. E. M. Tanke, Hans J. Cell Oncol Review The presence of tumor cells in bone marrow, peripheral blood and lymph nodes has proven its clinical and prognostic value. Since the frequency of these cells in bone marrow and blood is sometimes as low as 1 per million and due to the fact that for the analysis of lymph nodes many sectioning levels have to be analyzed, automated imaging devices have been suggested as an useful alternative to conventional manual screening of specimens. The aim of this paper is to review the performance of current equipment that is commercially available, based on literature published so far. Requirements for introducing this equipment for routine clinical practice are discussed. IOS Press 2006 2006-09-20 /pmc/articles/PMC4615155/ /pubmed/16988469 http://dx.doi.org/10.1155/2006/610562 Text en Copyright © 2006 Hindawi Publishing Corporation and the authors. |
spellingShingle | Review Mesker, Wilma E. Vrolijk, Hans Sloos, Willem C. R. Tollenaar, Rob A. E. M. Tanke, Hans J. Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices |
title | Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices |
title_full | Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices |
title_fullStr | Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices |
title_full_unstemmed | Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices |
title_short | Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices |
title_sort | detection of tumor cells in bone marrow, peripheral blood and lymph nodes by automated imaging devices |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615155/ https://www.ncbi.nlm.nih.gov/pubmed/16988469 http://dx.doi.org/10.1155/2006/610562 |
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