Detection of HER2 Amplification in Breast Carcinomas: Comparison of Multiplex Ligation-Dependent Probe Amplification (MLPA) and Fluorescence In Situ Hybridization (FISH) combined with Automated Spot Counting

In this study the detection of HER2 gene amplification was evaluated using Fluorescence In Situ Hybridization (FISH; PathVysion) in comparison with Multiplex Ligation-dependent Probe Amplification (MLPA), a PCR based technique. These two methods were evaluated on a series of 46 formalin fixed paraff...

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Autores principales: Moerland, Elna, van Hezik, Rens L. H. P. M., van der Aa, Toine C. J. M., van Beek, Mike W. P. M., van den Brule, Adriaan J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2006
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615166/
https://www.ncbi.nlm.nih.gov/pubmed/16988470
http://dx.doi.org/10.1155/2006/741586

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