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K-ras2 Activation and Genome Instability Increase Proliferation and Size of FAP Adenomas

The possible role of K‐ras2 mutations and aneuploidy toward increase of proliferation and adenoma size in Familial Adenomatous Polyposis (FAP) adenomas is not known. The present study addresses these issues by investigating 147 colorectal adenomas obtained from four FAP patients. The majority of ade...

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Detalles Bibliográficos
Autores principales: Rapallo, Anna, Sciutto, Andrea, Geido, Elio, Orecchia, Roberto, Infusini, Edmondo, Pujic, Natalija, d’Amore, Emanuele S.G., Monaco, Roberto, Risio, Mauro, Rossini, Francesco P., Giaretti, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615181/
https://www.ncbi.nlm.nih.gov/pubmed/10661623
http://dx.doi.org/10.1155/1999/257265

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