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K-ras2 Activation and Genome Instability Increase Proliferation and Size of FAP Adenomas
The possible role of K‐ras2 mutations and aneuploidy toward increase of proliferation and adenoma size in Familial Adenomatous Polyposis (FAP) adenomas is not known. The present study addresses these issues by investigating 147 colorectal adenomas obtained from four FAP patients. The majority of ade...
Autores principales: | Rapallo, Anna, Sciutto, Andrea, Geido, Elio, Orecchia, Roberto, Infusini, Edmondo, Pujic, Natalija, d’Amore, Emanuele S.G., Monaco, Roberto, Risio, Mauro, Rossini, Francesco P., Giaretti, Walter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615181/ https://www.ncbi.nlm.nih.gov/pubmed/10661623 http://dx.doi.org/10.1155/1999/257265 |
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