Breakdown of Epithelial Barrier Integrity and Overdrive Activation of Alveolar Epithelial Cells in the Pathogenesis of Acute Respiratory Distress Syndrome and Lung Fibrosis

Individual alveolar epithelial cells (AECs) collaboratively form a tight barrier between atmosphere and fluid-filled tissue to enable normal gas exchange. The tight junctions of AECs provide intercellular sealing and are integral to the maintenance of the AEC barrier integrity. Disruption and failur...

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Detalles Bibliográficos
Autores principales: Yanagi, Shigehisa, Tsubouchi, Hironobu, Miura, Ayako, Matsumoto, Nobuhiro, Nakazato, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615219/
https://www.ncbi.nlm.nih.gov/pubmed/26523279
http://dx.doi.org/10.1155/2015/573210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615219/
https://www.ncbi.nlm.nih.gov/pubmed/26523279
http://dx.doi.org/10.1155/2015/573210

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