Cargando…

Breakdown of Epithelial Barrier Integrity and Overdrive Activation of Alveolar Epithelial Cells in the Pathogenesis of Acute Respiratory Distress Syndrome and Lung Fibrosis

Individual alveolar epithelial cells (AECs) collaboratively form a tight barrier between atmosphere and fluid-filled tissue to enable normal gas exchange. The tight junctions of AECs provide intercellular sealing and are integral to the maintenance of the AEC barrier integrity. Disruption and failur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yanagi, Shigehisa, Tsubouchi, Hironobu, Miura, Ayako, Matsumoto, Nobuhiro, Nakazato, Masamitsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615219/ https://www.ncbi.nlm.nih.gov/pubmed/26523279 http://dx.doi.org/10.1155/2015/573210

Ejemplares similares

Desquamative interstitial pneumonia complicated by diffuse alveolar haemorrhage
por: Matsuo, Ayako, et al.
Publicado: (2017)

The Impacts of Cellular Senescence in Elderly Pneumonia and in Age-Related Lung Diseases That Increase the Risk of Respiratory Infections
por: Yanagi, Shigehisa, et al.
Publicado: (2017)

Allergic bronchopulmonary aspergillosis complicated by eosinophilic chronic rhinosinusitis successfully treated with mepolizumab
por: Matsumoto, Nobuhiro, et al.
Publicado: (2019)

Successful treatment of sepsis due to Pantoea agglomerans by polymyxin B-immobilized fiber column direct hemoperfusion therapy in a small cell lung carcinoma patient
por: Tsubouchi, Hironobu, et al.
Publicado: (2016)

Successful treatment of steroid-refractory double-positive ANCA and anti-GBM disease with a combination of plasma exchange and immunosuppression: A case report and literature review
por: Uto, Kazuko, et al.
Publicado: (2018)

Successful treatment of chronic lower respiratory tract infection by macrolide administration in a patient with intralobar pulmonary sequestration and primary ciliary dyskinesia
por: Tsubouchi, Hironobu, et al.
Publicado: (2015)

A case of impaired consciousness due to large cystic metastatic brain tumors from lung adenocarcinoma successfully controlled with Ommaya reservoir placement
por: Horiguchi, Takanori, et al.
Publicado: (2020)

Successful treatment with mepolizumab in a case of allergic bronchopulmonary aspergillosis complicated with nontuberculous mycobacterial infection
por: Tsubouchi, Hironobu, et al.
Publicado: (2019)

A case of bilateral invasive mucinous adenocarcinoma of the lung with severe productive cough and dyspnea successfully treated with palliative lung lobectomy
por: Horiguchi, Takanori, et al.
Publicado: (2021)

Transition From Distinct Types of KRAS Mutation-Harboring Multifocal Lung Adenocarcinoma to Rhabdoid Tumor: A Longitudinal Follow-Up
por: Setoguchi, Kensuke, et al.
Publicado: (2021)

Clinico-radiologic Characteristics of Pulmonary Visceral Larva Migrans Caused by Ascaris suum
por: Matsumoto, Nobuhiro, et al.
Publicado: (2021)

Alveolar epithelial glycocalyx shedding aggravates the epithelial barrier and disrupts epithelial tight junctions in acute respiratory distress syndrome
por: Li, Jun, et al.
Publicado: (2021)

Regeneration or Repair? The Role of Alveolar Epithelial Cells in the Pathogenesis of Idiopathic Pulmonary Fibrosis (IPF)
por: Confalonieri, Paola, et al.
Publicado: (2022)

Ventricular overdrive pacing during supraventricular tachycardia
por: Jain, Ashish, et al.
Publicado: (2022)

Antibiotic stewardship in the ICU: time to shift into overdrive
por: Mokrani, David, et al.
Publicado: (2023)

Role of various imbalances centered on alveolar epithelial cell/fibroblast apoptosis imbalance in the pathogenesis of idiopathic pulmonary fibrosis
por: Wang, Qing, et al.
Publicado: (2021)

Paracrine SPARC signaling dysregulates alveolar epithelial barrier integrity and function in lung fibrosis
por: Conforti, Franco, et al.
Publicado: (2020)

Hippo signaling impairs alveolar epithelial regeneration in pulmonary fibrosis
por: Warren, Rachel, et al.
Publicado: (2023)

Alveolar Epithelial Denudation Is a Major Factor in the Pathogenesis of Pleuroparenchymal Fibroelastosis
por: Zaizen, Yoshiaki, et al.
Publicado: (2021)

Epithelial–Mesenchymal Transition in the Pathogenesis of Idiopathic Pulmonary Fibrosis
por: Salton, Francesco, et al.
Publicado: (2019)

Alveolar Epithelial Type II Cells as Drivers of Lung Fibrosis in Idiopathic Pulmonary Fibrosis
por: Parimon, Tanyalak, et al.
Publicado: (2020)

Potential contribution of alveolar epithelial type I cells to pulmonary fibrosis
por: Kasper, Michael, et al.
Publicado: (2017)

Efferocytosis of apoptotic alveolar epithelial cells is sufficient to initiate lung fibrosis
por: Kim, Kevin K., et al.
Publicado: (2018)

Enteric Glia Cells Attenuate Cytomix-Induced Intestinal Epithelial Barrier Breakdown
por: Cheadle, Gerald A., et al.
Publicado: (2013)

Isolation of human β-defensin-4 in lung tissue and its increase in lower respiratory tract infection
por: Yanagi, Shigehisa, et al.
Publicado: (2005)

RAT Coronavirus Infection of Primary RAT Alveolar Epithelial Cells
por: Holmes, Kathryn V., et al.
Publicado: (2006)

Effects of hypoxia on bronchial and alveolar epithelial cells linked to pathogenesis in chronic lung disorders
por: Berggren-Nylund, Rebecca, et al.
Publicado: (2023)

The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis
por: Kim, Seok-Jo, et al.
Publicado: (2015)

Loss of MT1-MMP in Alveolar Epithelial Cells Exacerbates Pulmonary Fibrosis
por: Placido, Luis, et al.
Publicado: (2021)

KLF4 regulates TERT expression in alveolar epithelial cells in pulmonary fibrosis
por: Wang, Hui, et al.
Publicado: (2022)

Alveolar type 2 epithelial cell senescence and radiation-induced pulmonary fibrosis
por: Zhou, Shenghui, et al.
Publicado: (2022)

Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells
por: Kawanami, Yukiko, et al.
Publicado: (2009)

Extracellular Vesicles and Alveolar Epithelial-Capillary Barrier Disruption in Acute Respiratory Distress Syndrome: Pathophysiological Role and Therapeutic Potential
por: Esquivel-Ruiz, Sergio, et al.
Publicado: (2021)

Proteasome dysfunction in alveolar type 2 epithelial cells is associated with acute respiratory distress syndrome
por: Sitaraman, Sneha, et al.
Publicado: (2019)

Alveolar epithelial glycocalyx degradation mediates surfactant dysfunction and contributes to acute respiratory distress syndrome
por: Rizzo, Alicia N., et al.
Publicado: (2022)

Freedom to change: four strategies to put your inner drive into overdrive
por: Fullan, Michael
Publicado: (2015)

Resistant Ventricular Arrhythmia and the Role of Overdrive Pacing in the Suppression of the Electrical Storm
por: Magdi, Mohamed, et al.
Publicado: (2019)

Overdrive pacing of spiral waves in a model of human ventricular tissue
por: Pravdin, Sergei F., et al.
Publicado: (2020)

Dysregulated cross-talk between alveolar epithelial cells and stromal cells in idiopathic pulmonary fibrosis reduces epithelial regenerative capacity
por: Wisman, Marissa, et al.
Publicado: (2023)

Host-pathogen interactions during coronavirus infection of primary alveolar epithelial cells
por: Miura, Tanya A, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_qf5ck80pibplhbos2eh16hthh8