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Smart functional nucleic acid chimeras: Enabling tissue specific RNA targeting therapy

A major obstacle for effective utilization of therapeutic oligonucleotides such as siRNA, antisense, antimiRs etc. is to deliver them specifically to the target tissues. Toward this goal, nucleic acid aptamers are re-emerging as a prominent class of biomolecules capable of delivering target specific...

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Detalles Bibliográficos
Autores principales: Aaldering, Lukas J, Tayeb, Hossam, Krishnan, Shilpa, Fletcher, Susan, Wilton, Stephen D, Veedu, Rakesh N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615226/
https://www.ncbi.nlm.nih.gov/pubmed/25849197
http://dx.doi.org/10.1080/15476286.2015.1017234