Cargando…
Smart functional nucleic acid chimeras: Enabling tissue specific RNA targeting therapy
A major obstacle for effective utilization of therapeutic oligonucleotides such as siRNA, antisense, antimiRs etc. is to deliver them specifically to the target tissues. Toward this goal, nucleic acid aptamers are re-emerging as a prominent class of biomolecules capable of delivering target specific...
Autores principales: | Aaldering, Lukas J, Tayeb, Hossam, Krishnan, Shilpa, Fletcher, Susan, Wilton, Stephen D, Veedu, Rakesh N |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615226/ https://www.ncbi.nlm.nih.gov/pubmed/25849197 http://dx.doi.org/10.1080/15476286.2015.1017234 |
Ejemplares similares
-
Rational Design of Short Locked Nucleic Acid-Modified 2′-O-Methyl Antisense Oligonucleotides for Efficient Exon-Skipping In Vitro
por: Le, Bao T., et al.
Publicado: (2017) -
Nucleic acid visualization with UCSF Chimera
por: Couch, Gregory S., et al.
Publicado: (2006) -
Radiolabeling of Nucleic Acid Aptamers for Highly Sensitive Disease-Specific Molecular Imaging
por: Hassanzadeh, Leila, et al.
Publicado: (2018) -
In vitro evolution of chemically-modified nucleic acid aptamers: Pros and cons, and comprehensive selection strategies
por: Lipi, Farhana, et al.
Publicado: (2016) -
Unlocked nucleic acid modified primer-based enzymatic polymerization assay: towards allele-specific genotype detection of human platelet antigens
por: Le, Bao T., et al.
Publicado: (2018)