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The Aplidin analogs PM01215 and PM02781 inhibit angiogenesis in vitro and in vivo

BACKGROUND: Novel synthesized analogs of Aplidin, PM01215 and PM02781, were tested for antiangiogenic effects on primary human endothelial cells in vitro and for inhibition of angiogenesis and tumor growth in vivo. METHODS: Antiangiogenic activity of both derivatives was evaluated by real-time cell...

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Detalles Bibliográficos
Autores principales:	Borjan, Bojana, Steiner, Normann, Karbon, Silvia, Kern, Johann, Francesch, Andrés, Hermann, Martin, Willenbacher, Wolfgang, Gunsilius, Eberhard, Untergasser, Gerold
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615365/ https://www.ncbi.nlm.nih.gov/pubmed/26483043 http://dx.doi.org/10.1186/s12885-015-1729-4

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