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β-Catenin is required for the differentiation of iNKT2 and iNKT17 cells that augment IL-25-dependent lung inflammation
BACKGROUND: Invariant Natural Killer T (iNKT) cells have been implicated in lung inflammation in humans and also shown to be a key cell type in inducing allergic lung inflammation in mouse models. iNKT cells differentiate and acquire functional characteristics during development in the thymus. Howev...
Autores principales: | Berga-Bolaños, Rosa, Sharma, Archna, Steinke, Farrah C., Pyaram, Kalyani, Kim, Yeung-Hyen, Sultana, Dil A., Fang, Jessie X., Chang, Cheong-Hee, Xue, Hai-Hui, Heller, Nicola M., Sen, Jyoti Misra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615569/ https://www.ncbi.nlm.nih.gov/pubmed/26482437 http://dx.doi.org/10.1186/s12865-015-0121-0 |
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