Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study

Fibrinolytic therapy of venous thromboembolism (VTE) is increasingly utilized, yet limited knowledge is available regarding in vivo mechanisms that govern fibrinolytic efficacy. In particular, it is unknown how age-dependent thrombus organization limits direct blood contact with fibrin, the target o...

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Detalles Bibliográficos
Autores principales: Stein-Merlob, Ashley F., Kessinger, Chase W., Erdem, S. Sibel, Zelada, Henry, Hilderbrand, Scott A., Lin, Charles P., Tearney, Guillermo J., Jaff, Michael R., Reed, Guy L., Henke, Peter K., McCarthy, Jason R., Jaffer, Farouc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615735/
https://www.ncbi.nlm.nih.gov/pubmed/26516370
http://dx.doi.org/10.7150/thno.12494

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