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Reprogramming of fibroblast nuclei in cloned bovine embryos involves major structural remodeling with both striking similarities and differences to nuclear phenotypes of in vitro fertilized embryos
Nuclear landscapes were studied during preimplantation development of bovine embryos, generated either by in vitro fertilization (IVF), or generated as cloned embryos by somatic cell nuclear transfer (SCNT) of bovine fetal fibroblasts, using 3-dimensional confocal laser scanning microscopy (3D-CLSM)...
Autores principales: | Popken, Jens, Brero, Alessandro, Koehler, Daniela, Schmid, Volker J, Strauss, Axel, Wuensch, Annegret, Guengoer, Tuna, Graf, Alexander, Krebs, Stefan, Blum, Helmut, Zakhartchenko, Valeri, Wolf, Eckhard, Cremer, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615760/ https://www.ncbi.nlm.nih.gov/pubmed/25482066 http://dx.doi.org/10.4161/19491034.2014.979712 |
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