Cargando…
DNA double strand break repair pathway choice: a chromatin based decision?
DNA double-strand breaks (DSBs) are highly toxic lesions that can be rapidly repaired by 2 main pathways, namely Homologous Recombination (HR) and Non Homologous End Joining (NHEJ). The choice between these pathways is a critical, yet not completely understood, aspect of DSB repair. We recently foun...
Autores principales: | Clouaire, T, Legube, G |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615830/ https://www.ncbi.nlm.nih.gov/pubmed/25675367 http://dx.doi.org/10.1080/19491034.2015.1010946 |
Ejemplares similares
-
Genomic and chromatin features shaping meiotic double-strand break formation and repair in mice
por: Yamada, Shintaro, et al.
Publicado: (2017) -
Homologous chromosomes move and rapidly initiate contact at the sites of double-strand breaks in genes in G₀-phase human cells
por: Gandhi, Manoj, et al.
Publicado: (2013) -
From dynamic chromatin architecture to DNA damage repair and back
por: Fabre, Emmanuelle, et al.
Publicado: (2018) -
Comprehensive Mapping of Histone Modifications at DNA Double-Strand Breaks Deciphers Repair Pathway Chromatin Signatures
por: Clouaire, Thomas, et al.
Publicado: (2018) -
Gearing up chromatin: A role for chromatin remodeling during the transcriptional restart upon DNA damage
por: Mandemaker, Imke K, et al.
Publicado: (2014)