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Mechanisms of blood homeostasis: lineage tracking and a neutral model of cell populations in rhesus macaques
BACKGROUND: How a potentially diverse population of hematopoietic stem cells (HSCs) differentiates and proliferates to supply more than 10(11) mature blood cells every day in humans remains a key biological question. We investigated this process by quantitatively analyzing the clonal structure of pe...
Autores principales: | Goyal, Sidhartha, Kim, Sanggu, Chen, Irvin SY, Chou, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615871/ https://www.ncbi.nlm.nih.gov/pubmed/26486451 http://dx.doi.org/10.1186/s12915-015-0191-8 |
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