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The integrity of the G2421-C2395 base pair in the ribosomal E-site is crucial for protein synthesis
During the elongation cycle of protein biosynthesis, tRNAs traverse through the ribosome by consecutive binding to the 3 ribosomal binding sites (A-, P-, and E- sites). While the ribosomal A- and P-sites have been functionally well characterized in the past, the contribution of the E-site to protein...
Autores principales: | Koch, Miriam, Clementi, Nina, Rusca, Nicola, Vögele, Paul, Erlacher, Matthias, Polacek, Norbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615901/ https://www.ncbi.nlm.nih.gov/pubmed/25826414 http://dx.doi.org/10.1080/15476286.2015.1017218 |
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