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Synthetic self-adjuvanting glycopeptide cancer vaccines
Due to changes in glycosyltransferase expression during oncogenesis, the glycoproteins of cancer cells often carry highly truncated carbohydrate chains compared to those on healthy cells. These glycans are known as tumor-associated carbohydrate antigens (TACAs), and are prime targets for use in vacc...
Autores principales: | McDonald, David M., Byrne, Scott N., Payne, Richard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615963/ https://www.ncbi.nlm.nih.gov/pubmed/26557640 http://dx.doi.org/10.3389/fchem.2015.00060 |
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