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Synthetic self-adjuvanting glycopeptide cancer vaccines

Due to changes in glycosyltransferase expression during oncogenesis, the glycoproteins of cancer cells often carry highly truncated carbohydrate chains compared to those on healthy cells. These glycans are known as tumor-associated carbohydrate antigens (TACAs), and are prime targets for use in vacc...

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Detalles Bibliográficos
Autores principales: McDonald, David M., Byrne, Scott N., Payne, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615963/
https://www.ncbi.nlm.nih.gov/pubmed/26557640
http://dx.doi.org/10.3389/fchem.2015.00060

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