Intratumor Heterogeneity of K-Ras and p53 Mutations among Human Colorectal Adenomas Containing Early Cancer

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The molecular pathways and the timing of genetic events during human colorectal carcinogenesis are still not fully understood. We have addressed the intratumor heterogeneity of the mutational status of the k‐ras oncogene and of the p53 oncosuppressor gene during the adenoma–carcinoma sequence by inv...

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Detalles Bibliográficos
Autores principales: Giaretti, Walter, Macciocu, Barbara, Geido, Elio, Hermsen, Mario, Postma, Cindy, Baak, Jan, Williams, Richard, Meijer, Gerrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2000
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615987/
https://www.ncbi.nlm.nih.gov/pubmed/11310641
http://dx.doi.org/10.1155/2000/747524

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