Chronic Activation of the Renin-Angiotensin System Induces Lung Fibrosis

Pulmonary fibrosis is a serious lung disorder that can lead to respiratory failure. Here we show that transgenic mice expressing active renin from the liver (RenTgMK) developed progressive pulmonary fibrosis leading to impaired pulmonary function. Histological analyses revealed a marked increase in...

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Detalles Bibliográficos
Autores principales: Wang, Jiaolong, Chen, Li, Chen, Bohao, Meliton, Angelo, Liu, Shu Q., Shi, Yongyan, Liu, Tianjing, Deb, Dilip K., Solway, Julian, Chun Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616037/
https://www.ncbi.nlm.nih.gov/pubmed/26494430
http://dx.doi.org/10.1038/srep15561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616037/
https://www.ncbi.nlm.nih.gov/pubmed/26494430
http://dx.doi.org/10.1038/srep15561

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