Cargando…
Chronic Activation of the Renin-Angiotensin System Induces Lung Fibrosis
Pulmonary fibrosis is a serious lung disorder that can lead to respiratory failure. Here we show that transgenic mice expressing active renin from the liver (RenTgMK) developed progressive pulmonary fibrosis leading to impaired pulmonary function. Histological analyses revealed a marked increase in...
Autores principales: | Wang, Jiaolong, Chen, Li, Chen, Bohao, Meliton, Angelo, Liu, Shu Q., Shi, Yongyan, Liu, Tianjing, Deb, Dilip K., Solway, Julian, Chun Li, Yan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616037/ https://www.ncbi.nlm.nih.gov/pubmed/26494430 http://dx.doi.org/10.1038/srep15561 |
Ejemplares similares
-
Activation of the Renin-Angiotensin System Promotes Colitis Development
por: Shi, Yongyan, et al.
Publicado: (2016) -
Chronic vitamin D deficiency induces lung fibrosis through activation of the renin-angiotensin system
por: Shi, Yongyan, et al.
Publicado: (2017) -
Therapeutic effect of renin angiotensin system inhibitors on liver fibrosis
por: Zhu, Qianqian, et al.
Publicado: (2016) -
Vitamin D suppresses bleomycin-induced pulmonary fibrosis by targeting the local renin–angiotensin system in the lung
por: Chang, Jianjun, et al.
Publicado: (2021) -
The Role of the Renin-Angiotensin System in Hepatic Fibrosis
por: Lubel, J.S., et al.
Publicado: (2007)