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Treatment for Malignant Struma Ovarii in the Eyes of Thyroid Surgeons: A Case Report and Study of Chinese Cases Reported in the Literature

Malignant struma ovarii (MSO) is a rare malignant ovarian germ cell tumor that has been scarcely reported by thyroid surgeons focusing on treatment. There are no golden standards for its treatment. There has not been any Chinese case included in the English language literatures. This is the first st...

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Autores principales: Luo, Jiang-rong, Xie, Chun-bao, Li, Zhi-hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616397/
https://www.ncbi.nlm.nih.gov/pubmed/25474425
http://dx.doi.org/10.1097/MD.0000000000000147
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author Luo, Jiang-rong
Xie, Chun-bao
Li, Zhi-hui
author_facet Luo, Jiang-rong
Xie, Chun-bao
Li, Zhi-hui
author_sort Luo, Jiang-rong
collection PubMed
description Malignant struma ovarii (MSO) is a rare malignant ovarian germ cell tumor that has been scarcely reported by thyroid surgeons focusing on treatment. There are no golden standards for its treatment. There has not been any Chinese case included in the English language literatures. This is the first study by collecting all Chinese cases with clinical information. We emphasize on using I(131) therapy after operation. Presented is a case of struma ovarii with malignant histologic features who underwent definitive initial surgery of reproductive system tumors and a total thyroidectomy combined with thyroid-stimulating hormone (TSH)-suppressive therapy following treatment with I(131). Furthermore, a Chinese full-text database literature search for cases of MSO was performed, and advisable clinical data were collected following our treatment advice. Clinical data from 34 additional cases were compiled. As Chinese genetic background and environment are different from those of Western countries, our clinical data closely mirror theirs in some aspects. In addition, we provide a rare gene mutation type of MSO by the case from our department. Integrating literatures with the experience of thyroid surgeons, we recommend “multidisciplinary joint treatment” for MSO, namely traditional radical initial surgery of ovarian cancer and a total thyroidectomy combined with TSH-suppressive therapy following treatment with I(131) for those who do not desire preservation of fertility.
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spelling pubmed-46163972015-10-27 Treatment for Malignant Struma Ovarii in the Eyes of Thyroid Surgeons: A Case Report and Study of Chinese Cases Reported in the Literature Luo, Jiang-rong Xie, Chun-bao Li, Zhi-hui Medicine (Baltimore) 5700 Malignant struma ovarii (MSO) is a rare malignant ovarian germ cell tumor that has been scarcely reported by thyroid surgeons focusing on treatment. There are no golden standards for its treatment. There has not been any Chinese case included in the English language literatures. This is the first study by collecting all Chinese cases with clinical information. We emphasize on using I(131) therapy after operation. Presented is a case of struma ovarii with malignant histologic features who underwent definitive initial surgery of reproductive system tumors and a total thyroidectomy combined with thyroid-stimulating hormone (TSH)-suppressive therapy following treatment with I(131). Furthermore, a Chinese full-text database literature search for cases of MSO was performed, and advisable clinical data were collected following our treatment advice. Clinical data from 34 additional cases were compiled. As Chinese genetic background and environment are different from those of Western countries, our clinical data closely mirror theirs in some aspects. In addition, we provide a rare gene mutation type of MSO by the case from our department. Integrating literatures with the experience of thyroid surgeons, we recommend “multidisciplinary joint treatment” for MSO, namely traditional radical initial surgery of ovarian cancer and a total thyroidectomy combined with TSH-suppressive therapy following treatment with I(131) for those who do not desire preservation of fertility. Wolters Kluwer Health 2014-12-05 /pmc/articles/PMC4616397/ /pubmed/25474425 http://dx.doi.org/10.1097/MD.0000000000000147 Text en © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins http://creativecommons.org/licenses/by-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0, which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author. http://creativecommons.org/licenses/by-nd/4.0
spellingShingle 5700
Luo, Jiang-rong
Xie, Chun-bao
Li, Zhi-hui
Treatment for Malignant Struma Ovarii in the Eyes of Thyroid Surgeons: A Case Report and Study of Chinese Cases Reported in the Literature
title Treatment for Malignant Struma Ovarii in the Eyes of Thyroid Surgeons: A Case Report and Study of Chinese Cases Reported in the Literature
title_full Treatment for Malignant Struma Ovarii in the Eyes of Thyroid Surgeons: A Case Report and Study of Chinese Cases Reported in the Literature
title_fullStr Treatment for Malignant Struma Ovarii in the Eyes of Thyroid Surgeons: A Case Report and Study of Chinese Cases Reported in the Literature
title_full_unstemmed Treatment for Malignant Struma Ovarii in the Eyes of Thyroid Surgeons: A Case Report and Study of Chinese Cases Reported in the Literature
title_short Treatment for Malignant Struma Ovarii in the Eyes of Thyroid Surgeons: A Case Report and Study of Chinese Cases Reported in the Literature
title_sort treatment for malignant struma ovarii in the eyes of thyroid surgeons: a case report and study of chinese cases reported in the literature
topic 5700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616397/
https://www.ncbi.nlm.nih.gov/pubmed/25474425
http://dx.doi.org/10.1097/MD.0000000000000147
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