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A Rare Case of Breast Malignant Phyllodes Tumor With Metastases to the Kidney: Case Report

Phyllodes tumors are rare breast neoplasms. Surgery is the treatment of choice. The role of postoperative radiotherapy and chemotherapy is still under dispute, as there are no equivocal prognostic factors. Treatment failure results in the occurrence of distant metastasis—mainly to the lungs, bones,...

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Autores principales: Karczmarek-Borowska, Bożenna, Bukala, Agnieszka, Syrek-Kaplita, Karolina, Ksiazek, Mariusz, Filipowska, Justyna, Gradalska-Lampart, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616438/
https://www.ncbi.nlm.nih.gov/pubmed/26287414
http://dx.doi.org/10.1097/MD.0000000000001312
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author Karczmarek-Borowska, Bożenna
Bukala, Agnieszka
Syrek-Kaplita, Karolina
Ksiazek, Mariusz
Filipowska, Justyna
Gradalska-Lampart, Monika
author_facet Karczmarek-Borowska, Bożenna
Bukala, Agnieszka
Syrek-Kaplita, Karolina
Ksiazek, Mariusz
Filipowska, Justyna
Gradalska-Lampart, Monika
author_sort Karczmarek-Borowska, Bożenna
collection PubMed
description Phyllodes tumors are rare breast neoplasms. Surgery is the treatment of choice. The role of postoperative radiotherapy and chemotherapy is still under dispute, as there are no equivocal prognostic factors. Treatment failure results in the occurrence of distant metastasis—mainly to the lungs, bones, liver, and brain. We have described the case of a woman with a malignant phyllodes tumor of the breast that was surgically treated. She did not receive adjuvant therapy because there is no consensus on the role of postoperative chemotherapy and radiotherapy. One year following the surgery, the patient had left-sided nephrectomy performed because of a rapidly growing tumor of the kidney. Renal cancer was suspected; however, a histopathological examination revealed that it was a metastatic phyllodes tumor. At the same time, the patient was diagnosed as having metastases in the other kidney, the lungs, liver, and bones. Our case report describes not only an unusual localization of the metastases (in the kidneys), but also failure of the chemotherapy and the aggressive course of malignant phyllodes tumor. Identification of patients with high risk for distant metastasis and the introduction of uniform rules for the management of adjuvant chemotherapy and radiotherapy would make planning treatment as efficacious as possible.
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spelling pubmed-46164382015-10-27 A Rare Case of Breast Malignant Phyllodes Tumor With Metastases to the Kidney: Case Report Karczmarek-Borowska, Bożenna Bukala, Agnieszka Syrek-Kaplita, Karolina Ksiazek, Mariusz Filipowska, Justyna Gradalska-Lampart, Monika Medicine (Baltimore) 5700 Phyllodes tumors are rare breast neoplasms. Surgery is the treatment of choice. The role of postoperative radiotherapy and chemotherapy is still under dispute, as there are no equivocal prognostic factors. Treatment failure results in the occurrence of distant metastasis—mainly to the lungs, bones, liver, and brain. We have described the case of a woman with a malignant phyllodes tumor of the breast that was surgically treated. She did not receive adjuvant therapy because there is no consensus on the role of postoperative chemotherapy and radiotherapy. One year following the surgery, the patient had left-sided nephrectomy performed because of a rapidly growing tumor of the kidney. Renal cancer was suspected; however, a histopathological examination revealed that it was a metastatic phyllodes tumor. At the same time, the patient was diagnosed as having metastases in the other kidney, the lungs, liver, and bones. Our case report describes not only an unusual localization of the metastases (in the kidneys), but also failure of the chemotherapy and the aggressive course of malignant phyllodes tumor. Identification of patients with high risk for distant metastasis and the introduction of uniform rules for the management of adjuvant chemotherapy and radiotherapy would make planning treatment as efficacious as possible. Wolters Kluwer Health 2015-08-21 /pmc/articles/PMC4616438/ /pubmed/26287414 http://dx.doi.org/10.1097/MD.0000000000001312 Text en Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle 5700
Karczmarek-Borowska, Bożenna
Bukala, Agnieszka
Syrek-Kaplita, Karolina
Ksiazek, Mariusz
Filipowska, Justyna
Gradalska-Lampart, Monika
A Rare Case of Breast Malignant Phyllodes Tumor With Metastases to the Kidney: Case Report
title A Rare Case of Breast Malignant Phyllodes Tumor With Metastases to the Kidney: Case Report
title_full A Rare Case of Breast Malignant Phyllodes Tumor With Metastases to the Kidney: Case Report
title_fullStr A Rare Case of Breast Malignant Phyllodes Tumor With Metastases to the Kidney: Case Report
title_full_unstemmed A Rare Case of Breast Malignant Phyllodes Tumor With Metastases to the Kidney: Case Report
title_short A Rare Case of Breast Malignant Phyllodes Tumor With Metastases to the Kidney: Case Report
title_sort rare case of breast malignant phyllodes tumor with metastases to the kidney: case report
topic 5700
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616438/
https://www.ncbi.nlm.nih.gov/pubmed/26287414
http://dx.doi.org/10.1097/MD.0000000000001312
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