Use of a Novel Integrase-Deficient Lentivirus for Targeted Anti-Cancer Therapy With Survivin Promoter-Driven Diphtheria Toxin A

As an immunotoxin, diphtheria toxin has been widely used in gene therapy and gene function assays for its roles in protein synthesis inhibition, and the aim of our study is to set up a nonintegrating lentiviral system for specific expression of diphtheria toxin A (DTA) used in cancer gene therapy. H...

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Detalles Bibliográficos
Autores principales: Lin, Baoshun, Gao, Anding, Zhang, Rui, Ma, Hongyu, Shen, Haifeng, Hu, Qiong, Zhang, Hua, Zhao, Meng, Lan, Xiaopeng, Liu, Kuancan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
5700
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616595/
https://www.ncbi.nlm.nih.gov/pubmed/26252309
http://dx.doi.org/10.1097/MD.0000000000001301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616595/
https://www.ncbi.nlm.nih.gov/pubmed/26252309
http://dx.doi.org/10.1097/MD.0000000000001301

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