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Novel Medical Therapy of Cesarean Scar Pregnancy With a Viable Embryo Combining Multidose Methotrexate and Mifepristone: A Case Report
An ectopic pregnancy is defined as cesarean scar pregnancy (CSP) when the products of conception are implanted within the myometrium in the area of a cesarean section scar. CSP can be a life-threatening condition and to date there is no clear consensus for CSP management. A medical approach joining...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616779/ https://www.ncbi.nlm.nih.gov/pubmed/26469907 http://dx.doi.org/10.1097/MD.0000000000001697 |
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author | Kalampokas, Emmanouil Boutas, Ioannis Panoulis, Konstantinos Kalampokas, Theodoros |
author_facet | Kalampokas, Emmanouil Boutas, Ioannis Panoulis, Konstantinos Kalampokas, Theodoros |
author_sort | Kalampokas, Emmanouil |
collection | PubMed |
description | An ectopic pregnancy is defined as cesarean scar pregnancy (CSP) when the products of conception are implanted within the myometrium in the area of a cesarean section scar. CSP can be a life-threatening condition and to date there is no clear consensus for CSP management. A medical approach joining high treatment rates with fertility preservation could be a safer and less invasive method of therapy. We present a case of CSP with a viable embryo that was successfully treated with a novel medical therapy combining multidose methotrexate (MTX) and mifepristone. No further additional invasive procedure was required since pregnancy products were dissolved and no major complications were experienced. Multidose MTX and mifepristone can be considered a safe and effective treatment for CSP. |
format | Online Article Text |
id | pubmed-4616779 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-46167792015-10-27 Novel Medical Therapy of Cesarean Scar Pregnancy With a Viable Embryo Combining Multidose Methotrexate and Mifepristone: A Case Report Kalampokas, Emmanouil Boutas, Ioannis Panoulis, Konstantinos Kalampokas, Theodoros Medicine (Baltimore) 5600 An ectopic pregnancy is defined as cesarean scar pregnancy (CSP) when the products of conception are implanted within the myometrium in the area of a cesarean section scar. CSP can be a life-threatening condition and to date there is no clear consensus for CSP management. A medical approach joining high treatment rates with fertility preservation could be a safer and less invasive method of therapy. We present a case of CSP with a viable embryo that was successfully treated with a novel medical therapy combining multidose methotrexate (MTX) and mifepristone. No further additional invasive procedure was required since pregnancy products were dissolved and no major complications were experienced. Multidose MTX and mifepristone can be considered a safe and effective treatment for CSP. Wolters Kluwer Health 2015-10-16 /pmc/articles/PMC4616779/ /pubmed/26469907 http://dx.doi.org/10.1097/MD.0000000000001697 Text en Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 5600 Kalampokas, Emmanouil Boutas, Ioannis Panoulis, Konstantinos Kalampokas, Theodoros Novel Medical Therapy of Cesarean Scar Pregnancy With a Viable Embryo Combining Multidose Methotrexate and Mifepristone: A Case Report |
title | Novel Medical Therapy of Cesarean Scar Pregnancy With a Viable Embryo Combining Multidose Methotrexate and Mifepristone: A Case Report |
title_full | Novel Medical Therapy of Cesarean Scar Pregnancy With a Viable Embryo Combining Multidose Methotrexate and Mifepristone: A Case Report |
title_fullStr | Novel Medical Therapy of Cesarean Scar Pregnancy With a Viable Embryo Combining Multidose Methotrexate and Mifepristone: A Case Report |
title_full_unstemmed | Novel Medical Therapy of Cesarean Scar Pregnancy With a Viable Embryo Combining Multidose Methotrexate and Mifepristone: A Case Report |
title_short | Novel Medical Therapy of Cesarean Scar Pregnancy With a Viable Embryo Combining Multidose Methotrexate and Mifepristone: A Case Report |
title_sort | novel medical therapy of cesarean scar pregnancy with a viable embryo combining multidose methotrexate and mifepristone: a case report |
topic | 5600 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616779/ https://www.ncbi.nlm.nih.gov/pubmed/26469907 http://dx.doi.org/10.1097/MD.0000000000001697 |
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