Drug-like analogues of the parasitic worm-derived immunomodulator ES-62 are therapeutic in the MRL/Lpr model of systemic lupus erythematosus

INTRODUCTION: ES-62, a phosphorylcholine (PC)-containing immunomodulator secreted by the parasitic worm Acanthocheilonema viteae, protects against nephritis in the MRL/Lpr mouse model of systemic lupus erythematosus (SLE). However, ES-62 is not suitable for development as a therapy and thus we have...

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Detalles Bibliográficos
Autores principales: Rodgers, D T, Pineda, M A, Suckling, C J, Harnett, W, Harnett, M M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Concise Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616909/
https://www.ncbi.nlm.nih.gov/pubmed/26085597
http://dx.doi.org/10.1177/0961203315591031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616909/
https://www.ncbi.nlm.nih.gov/pubmed/26085597
http://dx.doi.org/10.1177/0961203315591031

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