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Effect of tubeless percutaneous nephrolithotomy on early renal function: Does it deteriorate?

BACKGROUND: The impact of standard percutaneous nephrolithotomy (PCNL) on short or long-term renal function has been evaluated in many studies. We evaluated the effect of tubeless PCNL on early renal function. MATERIALS AND METHODS: A total of 117 patients referring to our university center for PCNL...

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Autores principales: Hosseini, Seyed Reza, Mohseni, Mohammad Ghasem, Roshan, Hamzeh, Alizadeh, Farshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616997/
https://www.ncbi.nlm.nih.gov/pubmed/26605229
http://dx.doi.org/10.4103/2277-9175.166144
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author Hosseini, Seyed Reza
Mohseni, Mohammad Ghasem
Roshan, Hamzeh
Alizadeh, Farshid
author_facet Hosseini, Seyed Reza
Mohseni, Mohammad Ghasem
Roshan, Hamzeh
Alizadeh, Farshid
author_sort Hosseini, Seyed Reza
collection PubMed
description BACKGROUND: The impact of standard percutaneous nephrolithotomy (PCNL) on short or long-term renal function has been evaluated in many studies. We evaluated the effect of tubeless PCNL on early renal function. MATERIALS AND METHODS: A total of 117 patients referring to our university center for PCNL were enrolled in the study if they were matched with the inclusion criteria. Serum creatinine and hemoglobin (Hb) levels were measured before PCNL and 6, 24, 48, and 72 h after the operation. Glomerular filtration rate (GFR) was calculated using Cockroft-Gault formula. RESULTS: There were 79 (67.5%) men and 38 women (32.5%) with the mean age of 49.94 years ranging from 18 to 80 years in the study group. The mean creatinine level elevated in the first 48 h after PCNL but it started to reduce on the 3(rd) day (mean preoperative creatinine level: 1.32 ± 0.18 mg/dL, mean creatinine level after 48 h: 1.59 ± 0.24 mg/dL, creatinine level after 72 h: 1.42 ± 0.21245 mg/dL) (P < 0.0001). GFR values had the same rise and fall pattern as serum creatinine level (mean preoperative GFR: 74.89 mL/min, mean GFR after 48 h: 64.04 mL/min, GFR after 72 h: 69.54 mL/min, P < 0.0001). PCNL also affected blood Hb level. The mean preoperative Hb level was 15.06 ± 0.87 g/dL and it significantly decreased to 13.09 ± 1.06 g/dL after the operation (P < 0.0005). CONCLUSIONS: Tubeless PCNL like standard PCNL decreases GFR in the very early postoperative days. It is recommended that factors that might have a negative impact on renal function during first few days after PCNL be avoided.
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spelling pubmed-46169972015-11-24 Effect of tubeless percutaneous nephrolithotomy on early renal function: Does it deteriorate? Hosseini, Seyed Reza Mohseni, Mohammad Ghasem Roshan, Hamzeh Alizadeh, Farshid Adv Biomed Res Original Article BACKGROUND: The impact of standard percutaneous nephrolithotomy (PCNL) on short or long-term renal function has been evaluated in many studies. We evaluated the effect of tubeless PCNL on early renal function. MATERIALS AND METHODS: A total of 117 patients referring to our university center for PCNL were enrolled in the study if they were matched with the inclusion criteria. Serum creatinine and hemoglobin (Hb) levels were measured before PCNL and 6, 24, 48, and 72 h after the operation. Glomerular filtration rate (GFR) was calculated using Cockroft-Gault formula. RESULTS: There were 79 (67.5%) men and 38 women (32.5%) with the mean age of 49.94 years ranging from 18 to 80 years in the study group. The mean creatinine level elevated in the first 48 h after PCNL but it started to reduce on the 3(rd) day (mean preoperative creatinine level: 1.32 ± 0.18 mg/dL, mean creatinine level after 48 h: 1.59 ± 0.24 mg/dL, creatinine level after 72 h: 1.42 ± 0.21245 mg/dL) (P < 0.0001). GFR values had the same rise and fall pattern as serum creatinine level (mean preoperative GFR: 74.89 mL/min, mean GFR after 48 h: 64.04 mL/min, GFR after 72 h: 69.54 mL/min, P < 0.0001). PCNL also affected blood Hb level. The mean preoperative Hb level was 15.06 ± 0.87 g/dL and it significantly decreased to 13.09 ± 1.06 g/dL after the operation (P < 0.0005). CONCLUSIONS: Tubeless PCNL like standard PCNL decreases GFR in the very early postoperative days. It is recommended that factors that might have a negative impact on renal function during first few days after PCNL be avoided. Medknow Publications & Media Pvt Ltd 2015-09-28 /pmc/articles/PMC4616997/ /pubmed/26605229 http://dx.doi.org/10.4103/2277-9175.166144 Text en Copyright: © 2015 Hosseini. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Original Article
Hosseini, Seyed Reza
Mohseni, Mohammad Ghasem
Roshan, Hamzeh
Alizadeh, Farshid
Effect of tubeless percutaneous nephrolithotomy on early renal function: Does it deteriorate?
title Effect of tubeless percutaneous nephrolithotomy on early renal function: Does it deteriorate?
title_full Effect of tubeless percutaneous nephrolithotomy on early renal function: Does it deteriorate?
title_fullStr Effect of tubeless percutaneous nephrolithotomy on early renal function: Does it deteriorate?
title_full_unstemmed Effect of tubeless percutaneous nephrolithotomy on early renal function: Does it deteriorate?
title_short Effect of tubeless percutaneous nephrolithotomy on early renal function: Does it deteriorate?
title_sort effect of tubeless percutaneous nephrolithotomy on early renal function: does it deteriorate?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616997/
https://www.ncbi.nlm.nih.gov/pubmed/26605229
http://dx.doi.org/10.4103/2277-9175.166144
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