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What are we waiting for? An argument for early surgery for spinal epidural abscesses

BACKGROUND: In the article: Timing and prognosis of surgery for spinal epidural abscess (SEA): A review, Epstein raises one major point; it is imperative that spinal surgeons “take back decision-making” from our medical cohorts and reinstitute early surgery (<24 h) to better treat SEAs. METHODS:...

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Autor principal: Epstein, Nancy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617012/
https://www.ncbi.nlm.nih.gov/pubmed/26605113
http://dx.doi.org/10.4103/2152-7806.166894
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author Epstein, Nancy E.
author_facet Epstein, Nancy E.
author_sort Epstein, Nancy E.
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description BACKGROUND: In the article: Timing and prognosis of surgery for spinal epidural abscess (SEA): A review, Epstein raises one major point; it is imperative that spinal surgeons “take back decision-making” from our medical cohorts and reinstitute early surgery (<24 h) to better treat SEAs. METHODS: Spine surgeons recognize the clinical triad (e.g., fever [50%], spinal pain [92–100%], and neurological deficits [47%]) for establishing the diagnosis of an SEA. We also appreciate the multiple major risk factors for developing SEA; diabetes (15–30%), elevated white blood cell count (>12.5), high C-reactive protein (>115), positive blood cultures, radiographic cord compression, and significant neurological deficits (e.g., 19–45%). RESULTS: Recognizing these risk factors should prompt early open surgery (<24 h from the onset of a neurological deficit). Open surgery better defines the correct/multiple organisms present, and immediately provides adequate/thorough neurological decompression (with fusion if unstable). Although minimally invasive surgery may suffice in select cases, too often it provides insufficient biopsy/culture/irrigation/decompression. Most critically, nonsurgical options result in unacceptably high failure rates (e.g., 41-42.5-75% requiring delayed surgery), while risking permanent paralysis (up to 22%), and death (up to 25%). CONCLUSION: As spine surgeons, we need to “take back decision-making” from our medical cohorts and advocate for early surgery to achieve better outcomes for our patients. Why should anyone accept the >41-42.5 to up to the 75% failure rate that accompanies the nonsurgical treatment of SEA, much less the >25% mortality rate?
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spelling pubmed-46170122015-11-24 What are we waiting for? An argument for early surgery for spinal epidural abscesses Epstein, Nancy E. Surg Neurol Int Surgical Neurology International: Spine BACKGROUND: In the article: Timing and prognosis of surgery for spinal epidural abscess (SEA): A review, Epstein raises one major point; it is imperative that spinal surgeons “take back decision-making” from our medical cohorts and reinstitute early surgery (<24 h) to better treat SEAs. METHODS: Spine surgeons recognize the clinical triad (e.g., fever [50%], spinal pain [92–100%], and neurological deficits [47%]) for establishing the diagnosis of an SEA. We also appreciate the multiple major risk factors for developing SEA; diabetes (15–30%), elevated white blood cell count (>12.5), high C-reactive protein (>115), positive blood cultures, radiographic cord compression, and significant neurological deficits (e.g., 19–45%). RESULTS: Recognizing these risk factors should prompt early open surgery (<24 h from the onset of a neurological deficit). Open surgery better defines the correct/multiple organisms present, and immediately provides adequate/thorough neurological decompression (with fusion if unstable). Although minimally invasive surgery may suffice in select cases, too often it provides insufficient biopsy/culture/irrigation/decompression. Most critically, nonsurgical options result in unacceptably high failure rates (e.g., 41-42.5-75% requiring delayed surgery), while risking permanent paralysis (up to 22%), and death (up to 25%). CONCLUSION: As spine surgeons, we need to “take back decision-making” from our medical cohorts and advocate for early surgery to achieve better outcomes for our patients. Why should anyone accept the >41-42.5 to up to the 75% failure rate that accompanies the nonsurgical treatment of SEA, much less the >25% mortality rate? Medknow Publications & Media Pvt Ltd 2015-10-08 /pmc/articles/PMC4617012/ /pubmed/26605113 http://dx.doi.org/10.4103/2152-7806.166894 Text en Copyright: © 2015 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Surgical Neurology International: Spine
Epstein, Nancy E.
What are we waiting for? An argument for early surgery for spinal epidural abscesses
title What are we waiting for? An argument for early surgery for spinal epidural abscesses
title_full What are we waiting for? An argument for early surgery for spinal epidural abscesses
title_fullStr What are we waiting for? An argument for early surgery for spinal epidural abscesses
title_full_unstemmed What are we waiting for? An argument for early surgery for spinal epidural abscesses
title_short What are we waiting for? An argument for early surgery for spinal epidural abscesses
title_sort what are we waiting for? an argument for early surgery for spinal epidural abscesses
topic Surgical Neurology International: Spine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617012/
https://www.ncbi.nlm.nih.gov/pubmed/26605113
http://dx.doi.org/10.4103/2152-7806.166894
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