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The lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain
Glycine transporter 1 (GlyT1) plays a crucial role in regulating extracellular glycine concentrations and might thereby constitute a new drug target for the modulation of glycinergic inhibition in pain signaling. Consistent with this view, inhibition of GlyT1 has been found to induce antinociceptive...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617288/ https://www.ncbi.nlm.nih.gov/pubmed/25932687 http://dx.doi.org/10.1097/j.pain.0000000000000206 |