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Chikungunya risk for Brazil
This study aimed to show, based on the literature on the subject, the potential for dispersal and establishment of the chikungunya virus in Brazil. The chikungunya virus, a Togaviridae member of the genus Alphavirus, reached the Americas in 2013 and, the following year, more than a million cases wer...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculdade de Saúde Pública da Universidade de São Paulo
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617438/ https://www.ncbi.nlm.nih.gov/pubmed/26398876 http://dx.doi.org/10.1590/S0034-8910.2015049006219 |
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author | Azevedo, Raimunda do Socorro da Silva Oliveira, Consuelo Silva Vasconcelos, Pedro Fernando da Costa |
author_facet | Azevedo, Raimunda do Socorro da Silva Oliveira, Consuelo Silva Vasconcelos, Pedro Fernando da Costa |
author_sort | Azevedo, Raimunda do Socorro da Silva |
collection | PubMed |
description | This study aimed to show, based on the literature on the subject, the potential for dispersal and establishment of the chikungunya virus in Brazil. The chikungunya virus, a Togaviridae member of the genus Alphavirus, reached the Americas in 2013 and, the following year, more than a million cases were reported. In Brazil, indigenous transmission was registered in Amapa and Bahia States, even during the period of low rainfall, exposing the whole country to the risk of virus spreading. Brazil is historically infested by Ae. aegypti and Ae. albopictus, also dengue vectors. Chikungunya may spread, and it is important to take measures to prevent the virus from becoming endemic in the country. Adequate care for patients with chikungunya fever requires training general practitioners, rheumatologists, nurses, and experts in laboratory diagnosis. Up to November 2014, more than 1,000 cases of the virus were reported in Brazil. There is a need for experimental studies in animal models to understand the dynamics of infection and the pathogenesis as well as to identify pathophysiological mechanisms that may contribute to identifying effective drugs against the virus. Clinical trials are needed to identify the causal relationship between the virus and serious injuries observed in different organs and joints. In the absence of vaccines or effective drugs against the virus, currently the only way to prevent the disease is vector control, which will also reduce the number of cases of dengue fever. |
format | Online Article Text |
id | pubmed-4617438 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Faculdade de Saúde Pública da Universidade de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-46174382015-11-05 Chikungunya risk for Brazil Azevedo, Raimunda do Socorro da Silva Oliveira, Consuelo Silva Vasconcelos, Pedro Fernando da Costa Rev Saude Publica Comments This study aimed to show, based on the literature on the subject, the potential for dispersal and establishment of the chikungunya virus in Brazil. The chikungunya virus, a Togaviridae member of the genus Alphavirus, reached the Americas in 2013 and, the following year, more than a million cases were reported. In Brazil, indigenous transmission was registered in Amapa and Bahia States, even during the period of low rainfall, exposing the whole country to the risk of virus spreading. Brazil is historically infested by Ae. aegypti and Ae. albopictus, also dengue vectors. Chikungunya may spread, and it is important to take measures to prevent the virus from becoming endemic in the country. Adequate care for patients with chikungunya fever requires training general practitioners, rheumatologists, nurses, and experts in laboratory diagnosis. Up to November 2014, more than 1,000 cases of the virus were reported in Brazil. There is a need for experimental studies in animal models to understand the dynamics of infection and the pathogenesis as well as to identify pathophysiological mechanisms that may contribute to identifying effective drugs against the virus. Clinical trials are needed to identify the causal relationship between the virus and serious injuries observed in different organs and joints. In the absence of vaccines or effective drugs against the virus, currently the only way to prevent the disease is vector control, which will also reduce the number of cases of dengue fever. Faculdade de Saúde Pública da Universidade de São Paulo 2015-09-29 /pmc/articles/PMC4617438/ /pubmed/26398876 http://dx.doi.org/10.1590/S0034-8910.2015049006219 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Comments Azevedo, Raimunda do Socorro da Silva Oliveira, Consuelo Silva Vasconcelos, Pedro Fernando da Costa Chikungunya risk for Brazil |
title | Chikungunya risk for Brazil |
title_full | Chikungunya risk for Brazil |
title_fullStr | Chikungunya risk for Brazil |
title_full_unstemmed | Chikungunya risk for Brazil |
title_short | Chikungunya risk for Brazil |
title_sort | chikungunya risk for brazil |
topic | Comments |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617438/ https://www.ncbi.nlm.nih.gov/pubmed/26398876 http://dx.doi.org/10.1590/S0034-8910.2015049006219 |
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