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Chikungunya risk for Brazil

This study aimed to show, based on the literature on the subject, the potential for dispersal and establishment of the chikungunya virus in Brazil. The chikungunya virus, a Togaviridae member of the genus Alphavirus, reached the Americas in 2013 and, the following year, more than a million cases wer...

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Autores principales: Azevedo, Raimunda do Socorro da Silva, Oliveira, Consuelo Silva, Vasconcelos, Pedro Fernando da Costa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculdade de Saúde Pública da Universidade de São Paulo 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617438/
https://www.ncbi.nlm.nih.gov/pubmed/26398876
http://dx.doi.org/10.1590/S0034-8910.2015049006219
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author Azevedo, Raimunda do Socorro da Silva
Oliveira, Consuelo Silva
Vasconcelos, Pedro Fernando da Costa
author_facet Azevedo, Raimunda do Socorro da Silva
Oliveira, Consuelo Silva
Vasconcelos, Pedro Fernando da Costa
author_sort Azevedo, Raimunda do Socorro da Silva
collection PubMed
description This study aimed to show, based on the literature on the subject, the potential for dispersal and establishment of the chikungunya virus in Brazil. The chikungunya virus, a Togaviridae member of the genus Alphavirus, reached the Americas in 2013 and, the following year, more than a million cases were reported. In Brazil, indigenous transmission was registered in Amapa and Bahia States, even during the period of low rainfall, exposing the whole country to the risk of virus spreading. Brazil is historically infested by Ae. aegypti and Ae. albopictus, also dengue vectors. Chikungunya may spread, and it is important to take measures to prevent the virus from becoming endemic in the country. Adequate care for patients with chikungunya fever requires training general practitioners, rheumatologists, nurses, and experts in laboratory diagnosis. Up to November 2014, more than 1,000 cases of the virus were reported in Brazil. There is a need for experimental studies in animal models to understand the dynamics of infection and the pathogenesis as well as to identify pathophysiological mechanisms that may contribute to identifying effective drugs against the virus. Clinical trials are needed to identify the causal relationship between the virus and serious injuries observed in different organs and joints. In the absence of vaccines or effective drugs against the virus, currently the only way to prevent the disease is vector control, which will also reduce the number of cases of dengue fever.
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spelling pubmed-46174382015-11-05 Chikungunya risk for Brazil Azevedo, Raimunda do Socorro da Silva Oliveira, Consuelo Silva Vasconcelos, Pedro Fernando da Costa Rev Saude Publica Comments This study aimed to show, based on the literature on the subject, the potential for dispersal and establishment of the chikungunya virus in Brazil. The chikungunya virus, a Togaviridae member of the genus Alphavirus, reached the Americas in 2013 and, the following year, more than a million cases were reported. In Brazil, indigenous transmission was registered in Amapa and Bahia States, even during the period of low rainfall, exposing the whole country to the risk of virus spreading. Brazil is historically infested by Ae. aegypti and Ae. albopictus, also dengue vectors. Chikungunya may spread, and it is important to take measures to prevent the virus from becoming endemic in the country. Adequate care for patients with chikungunya fever requires training general practitioners, rheumatologists, nurses, and experts in laboratory diagnosis. Up to November 2014, more than 1,000 cases of the virus were reported in Brazil. There is a need for experimental studies in animal models to understand the dynamics of infection and the pathogenesis as well as to identify pathophysiological mechanisms that may contribute to identifying effective drugs against the virus. Clinical trials are needed to identify the causal relationship between the virus and serious injuries observed in different organs and joints. In the absence of vaccines or effective drugs against the virus, currently the only way to prevent the disease is vector control, which will also reduce the number of cases of dengue fever. Faculdade de Saúde Pública da Universidade de São Paulo 2015-09-29 /pmc/articles/PMC4617438/ /pubmed/26398876 http://dx.doi.org/10.1590/S0034-8910.2015049006219 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Comments
Azevedo, Raimunda do Socorro da Silva
Oliveira, Consuelo Silva
Vasconcelos, Pedro Fernando da Costa
Chikungunya risk for Brazil
title Chikungunya risk for Brazil
title_full Chikungunya risk for Brazil
title_fullStr Chikungunya risk for Brazil
title_full_unstemmed Chikungunya risk for Brazil
title_short Chikungunya risk for Brazil
title_sort chikungunya risk for brazil
topic Comments
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617438/
https://www.ncbi.nlm.nih.gov/pubmed/26398876
http://dx.doi.org/10.1590/S0034-8910.2015049006219
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